Comparing two types of CPAP machines for obstructive sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness and patient satisfaction of two CPAP machines, the AirSense 10 and the AirMini, in treating moderate to severe obstructive sleep apnea (OSA). Participants will undergo a sleep study to confirm their diagnosis and will then be randomized to use each CPAP device for a week. The study will assess overall satisfaction, apnea-hypopnea index (AHI) reduction, and other factors such as comfort and maintenance. Conducted at the National University of Malaysia, the trial will run from September 2024 to December 2026.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged ≥ 18 years.
* Patients diagnosed with moderate to severe OSA (based on AHI classification from sleep study performed).
* Patients who are able to understand and answer the questionnaire given.

Exclusion Criteria:

* Patients who are unable to give consent to the study.
* Patients who have been diagnosed with OSA and already on CPAP machine.
* Patients who had underlying Obesity Hypoventilation Syndrome (OHS).
* Patients who had underlying co-morbidities that worsen apnea symptoms, such as congestive cardiac failure, active malignancy, narcolepsy, active alcohol or drug abuse, treatment-refractory dementia, psychotic illness and active use of drugs that disturb the sleep architecture (i.e hypnotics or stimulants of central nervous system).

Where it's running

• National University of Malaysia, Faculty of Medicine
  Cheras, Kuala Lumpur, Malaysia Recruiting

Study contacts

• Principal investigator: Mohamed Faisal Abdul Hamid, MBBS(IIUM) — National University of Malaysia
• Study coordinator: Mohamed Faisal Abdul Hamid, MBBS(IIUM)
• Email: faisal.hamid@ppukm.ukm.edu.my
• Phone: 0391455555

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.