Comparing two types of airway clearance devices
Official title: Outcome Comparisons of Two Vibratory Positive Expiratory Pressure Devices in Patients Unable to Clear Airway Secretions
Run by Rush University Medical Center · NCT05873504 · Data updated 2026-11-12
This study is testing whether a high oscillatory airway clearance device works better than a low oscillatory one for helping adults clear mucus from their lungs.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 64 (estimated) |
| Sponsor | Rush University Medical Center Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | May 1, 2023 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | February 19, 2026 |
| Trial ID | NCT05873504 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 18 years or older with a RAAT score of at least 10 and a secretion score of at least 5.
✕Probably not a fit
Patients younger than 18, pregnant individuals, or those with severe respiratory limitations may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study is a randomized control trial that aims to compare the effectiveness of a high oscillatory index device versus a low oscillatory index device in clearing airway secretions in adult patients. Participants will be adults aged 18 and older who meet specific respiratory assessment criteria. After randomization, patients will receive instructions on how to use the assigned device, and their clinical outcomes will be monitored until discharge from the hospital. The primary outcome measured will be the RAAT score, which assesses various respiratory parameters.
Why it matters
Potential benefit: If successful, this study could improve airway clearance techniques for patients with respiratory impairments.
How similar studies have gone: Other studies have explored airway clearance devices, but this specific comparison of oscillatory index devices is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults 18 years or older * Respiratory assess and treat (RAAT) score of at least 10 and a secretion score of at least 5 Exclusion Criteria: * Younger than 18 years of age * Pregnant * Slow vital capacity (SVC) of \<10 mL/kg * Unable to follow instructions * Currently receiving cough assist, vest therapy or intrapulmonary percussive ventilation * Received more than 1 therapy session using oscillatory index device * Multiple ICU admission with previous study enrollment
Where it's running
-
Rush University Medical Center
Chicago, Illinois, United States Recruiting
Study contacts
- Study coordinator: Lauren Harnois, MSc
- Email: Lauren_J_Harnois@rush.edu
- Phone: 312-947-8898
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.