Comparing two treatments for moderate pulpitis in adult molars

COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS: RANDOMIZED CLINICAL TRIAL

Not applicable Interventional Postgraduate Institute of Dental Sciences Rohtak · NCT06447753

This study tests whether a direct pulp capping or a complete pulpotomy works better for adults with moderate pulpitis in their back teeth.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment92 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorPostgraduate Institute of Dental Sciences Rohtak Academic / other
Locations1 site (Rohtak, Haryana)
Trial IDNCT06447753 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of direct pulp capping versus complete pulpotomy in treating mature permanent mandibular molars diagnosed with moderate pulpitis. The study aims to determine which intervention leads to better healing outcomes by addressing the inflamed pulp tissue while eliminating the source of infection. Participants will undergo either treatment based on specific eligibility criteria, including age and dental condition. The trial will assess clinical responses and healing over time to provide insights into the best management strategies for this dental condition.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with restorable mature permanent mandibular molars exhibiting signs of moderate pulpitis.

Not a fit: Patients with immature roots, signs of pulpal necrosis, or significant medical histories that could complicate treatment may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve treatment outcomes for patients with moderate pulpitis, potentially preserving their teeth and reducing the need for more invasive procedures.

How similar studies have performed: Other studies have shown promising results with similar approaches in vital pulp therapy, suggesting that this trial is building on established concepts in dental treatment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1\. The patient should be ≥18 years of age. 2. Restorable mature permanent 1 st and 2nd Mandibular molars with extremely deep caries (≥2/3 dentine involvement) 3. Tooth should give positive response to pulp sensibility testing. 4. Clinical diagnosis of moderate pulpitis. 5. Radiographic finding of periapical index (PAI) score ≤2. 6. Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).

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Exclusion Criteria:

1. Teeth with immature roots.
2. No pulp exposure after caries excavation.
3. Bleeding could not be controlled in 6 minutes.
4. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.
5. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.
6. Internal/external resorption.
7. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine) -

Where this trial is running

Rohtak, Haryana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Moderate Pulpitis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.