Comparing two training methods for treating De Quervain Tenosynovitis

Comparison of Sub-maximal Voluntary Isometric Training vs Eccentric Training in Management of De Quervain Tenosynovitis

NA · Foundation University Islamabad · NCT06839690

This study is testing which of two training methods works better for people with De Quervain Tenosynovitis to help them feel better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment58 (estimated)
Ages21 Years to 50 Years
SexAll
SponsorFoundation University Islamabad (other)
Locations1 site (Rawalpindi, Punjab Province)
Trial IDNCT06839690 on ClinicalTrials.gov

What this trial studies

This study is a randomized control trial aimed at comparing the effects of Sub-maximal Voluntary Isometric Training and Eccentric Training in managing De Quervain Tenosynovitis. Participants will be assigned to either training group using a coin toss method. The effectiveness of the interventions will be assessed through specific tests, including the WHAT test, Finkelstein's test, and the De Quervain Screening Tool. The study is conducted at Foundation University College of Physical Therapy in Rawalpindi, Punjab.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 21-50 with a history of thumb pain and tenderness lasting 3 weeks or more.

Not a fit: Patients with conditions such as osteoarthritis, rheumatoid arthritis, or previous surgeries affecting the wrist may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide effective non-surgical treatment options for patients suffering from De Quervain Tenosynovitis.

How similar studies have performed: While there is limited data on the specific comparison of these two training methods, similar approaches in physical therapy have shown promise in managing musculoskeletal conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients having history of pain, tenderness in thumb region from 3 weeks or more
* Age 21-50
* Both genders
* Individuals meeting the diagnostic criteria i.e.
* A score of 3 or more out of 7 on De Quervain screening tool.
* Positive Wrist hyperflexion and abduction of thumb (WHAT) test
* Positive Finkelstein's / Eichhoff's test

Exclusion criteria:

* Diagnosed cases of Osteoarthritis of 1st CMC joint and Rheumatoid arthritis
* C6 cervical radiculopathy
* Any systemic inflammatory condition like septic arthritis
* Carpal Tunnel Syndrome
* Complex regional pain syndrome
* Previous surgery impacting the first extensor compartment of the wrist
* Corticosteroid injection in the radial wrist region within 3 months of enrolment into the study
* If patient had undergone isometric thumb exercises or any strengthening protocol lasting greater than 2 weeks for the management of their current episode of de Quervain's syndrome

Where this trial is running

Rawalpindi, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: De Quervain Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.