Clinical trial Recruiting at 1 site Interventional Ages 21 to 50

Comparing two training methods for treating De Quervain Tenosynovitis

Official title: Comparison of Sub-maximal Voluntary Isometric Training vs Eccentric Training in Management of De Quervain Tenosynovitis

Run by Foundation University Islamabad · NCT06839690 · Data updated 2026-11-12

This study is testing which of two training methods works better for people with De Quervain Tenosynovitis to help them feel better.

Quick facts

Study typeInterventional
Ages21 Years to 50 Years
SexAll
Enrollment58 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Rawalpindi, Punjab Province)
StatusRecruiting
StartedJuly 18, 2024
Main results expectedJune 1, 2025
Study endsJune 20, 2025
Registry record updatedFebruary 21, 2025
Trial IDNCT06839690 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 21-50 with a history of thumb pain and tenderness lasting 3 weeks or more.

Probably not a fit

Patients with conditions such as osteoarthritis, rheumatoid arthritis, or previous surgeries affecting the wrist may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study is a randomized control trial aimed at comparing the effects of Sub-maximal Voluntary Isometric Training and Eccentric Training in managing De Quervain Tenosynovitis. Participants will be assigned to either training group using a coin toss method. The effectiveness of the interventions will be assessed through specific tests, including the WHAT test, Finkelstein's test, and the De Quervain Screening Tool. The study is conducted at Foundation University College of Physical Therapy in Rawalpindi, Punjab.

Why it matters

Potential benefit: If successful, this study could provide effective non-surgical treatment options for patients suffering from De Quervain Tenosynovitis.

How similar studies have gone: While there is limited data on the specific comparison of these two training methods, similar approaches in physical therapy have shown promise in managing musculoskeletal conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients having history of pain, tenderness in thumb region from 3 weeks or more
* Age 21-50
* Both genders
* Individuals meeting the diagnostic criteria i.e.
* A score of 3 or more out of 7 on De Quervain screening tool.
* Positive Wrist hyperflexion and abduction of thumb (WHAT) test
* Positive Finkelstein's / Eichhoff's test

Exclusion criteria:

* Diagnosed cases of Osteoarthritis of 1st CMC joint and Rheumatoid arthritis
* C6 cervical radiculopathy
* Any systemic inflammatory condition like septic arthritis
* Carpal Tunnel Syndrome
* Complex regional pain syndrome
* Previous surgery impacting the first extensor compartment of the wrist
* Corticosteroid injection in the radial wrist region within 3 months of enrolment into the study
* If patient had undergone isometric thumb exercises or any strengthening protocol lasting greater than 2 weeks for the management of their current episode of de Quervain's syndrome

Where it's running

  • Foundation University College of Physcial Therapy
    Rawalpindi, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.