Comparing two techniques for treating ridge contour defects in the mouth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate and compare the effectiveness of a novel Denuded interpositional pedicled rolled flap technique (DIPRF) against the conventional subepithelial connective tissue graft technique for augmenting soft tissues in patients with ridge contour defects. Fifty patients with soft tissue defects in the maxillary premolar region will be randomly assigned to either the test group receiving DIPRF or the control group receiving the conventional graft. Clinical and radiographic assessments will be conducted to measure tissue volumetric changes and ridge thickness at various intervals post-surgery, alongside patient-reported outcomes regarding pain and satisfaction. The study will utilize advanced imaging techniques, including digitally calibrated casts and CBCT analysis, to ensure accurate evaluations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adults above the age of 18 to 50 years.
2. Males and females as confirmed by asking the female patients about whether they are pregnant or not
3. Patient's with Seibert classification class I requiring future rehabilitation of one or more premolar region and sound adjacent teeth.
4. Soft tissue thickness on the palatal tissues more than 6mm at the site of harvesting the graft.
5. Presence of Mandibular posterior teeth opposing the tooth to be replaced for occlusion.
6. Clinically healthy soft tissues with no signs of clinical pathology of the soft tissue.
7. Good oral hygiene.
8. Patient accepts to sign an informed consent.
9. ASA I or ASA II Patient.

Exclusion Criteria:

1. Patients with ridge defects due to bone defect
2. Smoker patients who smoke more than 10 cigarettes per day
3. Pregnant females

Where it's running

• Misr International University
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: Hebattallah A Mattar — Misr International University
• Study coordinator: Hebattallah A Mattar
• Email: hebatullah.mater@miuegypt.edu.eg
• Phone: 201207000253

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.