Comparing two techniques for facial symmetry after jaw reconstruction

Assessment of Facial Symmetry Following Fibula Free Flap Fixated in a Prosthetically Favorable Position Versus the Inferior Border Position for Mandibular Reconstruction: a Randomized Controlled Trial.

NA · Cairo University · NCT06790628

This study is testing two different ways to fix the jaw after reconstruction to see which one helps people have a more symmetrical face and feel happier with the results.

Quick facts

PhaseNA
Study typeInterventional
Enrollment26 (estimated)
SexAll
SponsorCairo University (other)
Locations1 site (Cairo, Cairo Governorate)
Trial IDNCT06790628 on ClinicalTrials.gov

What this trial studies

This study evaluates the outcomes of facial symmetry following mandibular reconstruction using fibula free flaps. It compares two fixation techniques: one at the alveolar level, which is considered prosthetically favorable, and the other at the inferior border level, which is the conventional approach. The study is designed as a randomized controlled trial with parallel groups, assessing patient satisfaction and symmetry over a 12-month follow-up period. Patients with significant mandibular defects due to various conditions will be enrolled to determine the effectiveness of each technique.

Who should consider this trial

Good fit: Ideal candidates are patients requiring mandibular reconstruction due to tumors, trauma, or osteomyelitis with defects greater than 9 cm.

Not a fit: Patients with systemic conditions that would contraindicate the surgical procedure may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve surgical techniques for mandibular reconstruction, leading to better facial symmetry and patient satisfaction.

How similar studies have performed: While similar studies have explored mandibular reconstruction techniques, this specific comparison of fixation positions is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient who requires mandibular resection due to tumor, trauma, osteomyelitis or osteoradionecrosis.
* Patient with Mandibular defect \>9 cm.

Exclusion Criteria:

\- Patients with systemic condition counteracting with the surgical procedure.

Where this trial is running

Cairo, Cairo Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Mandible Reconstruction, Segmental mandibular defect, mandibular reconstruction, fibula free flap, dental implants, facial symmetry, face scan.

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.