Comparing two suturing techniques for closing abdominal surgery wounds

The Comparison of Interrupted Modified Smead-Jones Versus Conventional Continuous Suturing Technique for Closure of Rectus Sheath in Patients Undergoing Laparotomy for Hollow Viscus Perforation.

Not applicable Interventional King Edward Medical University · NCT06697067

This study is testing whether a new way of stitching up surgery wounds works better than the traditional method for patients having emergency surgery for a perforated organ.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment108 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorKing Edward Medical University Academic / other
Locations1 site (Lahore, Punjab Province)
Trial IDNCT06697067 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effectiveness of the interrupted modified Smead-Jones suturing technique against the conventional continuous suturing technique for closing the rectus sheath in patients undergoing emergency laparotomy for hollow viscus perforation. A total of 108 patients aged 18 to 60 will be randomly assigned to one of the two suturing methods after undergoing necessary pre-operative assessments. The study will monitor outcomes related to wound dehiscence, a common complication that can lead to increased morbidity and prolonged hospital stays. The trial is conducted at King Edward Medical University and Mayo Hospital Lahore.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 60 who require emergency laparotomy for hollow viscus perforation.

Not a fit: Patients with a history of previous laparotomy or those presenting with abdominal wall injuries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients undergoing emergency laparotomy.

How similar studies have performed: Previous studies have shown varying success with different suturing techniques, but this specific comparison is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:All patients of both genders with age greater than 18 to 60 years, undergoing emergency laparotomy through midline incision for hollow viscus perforation.

ASA grade III -

Exclusion Criteria:Patients who had undergone a previous laparotomy for any condition or had an incisional hernia or burst abdomen at presentation.

Patients undergoing laparotomy with anterior abdominal wall injury in the form of muscle, hematoma, disruption or abdominal wall laceration.

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Where this trial is running

Lahore, Punjab Province

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Wound Dehiscence, SurgicalFarrukh 24
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.