Comparing two surgical techniques for vein extraction in heart surgery

Morbidity of Conventional and No-touch Saphenectomy in Coronary Artery Bypass Grafting, a Randomized Non-inferiority Clinical Trial

Not applicable Interventional Instituto Nacional de Cirugia Cardiaca, Uruguay · NCT06496321

This study is testing whether a new way of removing a vein for heart surgery causes fewer problems than the traditional method for patients having coronary bypass surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment52 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorInstituto Nacional de Cirugia Cardiaca, Uruguay Academic / other
Locations1 site (Montevideo)
Trial IDNCT06496321 on ClinicalTrials.gov

What this trial studies

This clinical research project aims to compare the morbidity associated with two surgical techniques for extracting the internal saphenous vein used in coronary artery bypass grafting. The study will evaluate the conventional saphenectomy technique against the no-touch saphenectomy technique, which has shown promising results in previous trials. A prospective randomized clinical trial will be conducted to assess various morbidity factors, including local infection and wound complications, in patients undergoing coronary revascularization. The goal is to demonstrate that the no-touch technique is not inferior to the conventional method in terms of wound morbidity.

Who should consider this trial

Good fit: Ideal candidates are patients scheduled for coronary revascularization surgery requiring the internal saphenous vein as a conduit.

Not a fit: Patients undergoing emergency surgeries or those with poor metabolic control or chronic venous insufficiency may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients undergoing coronary artery bypass grafting.

How similar studies have performed: Previous studies have indicated positive outcomes for the no-touch saphenectomy technique, suggesting potential for success in this comparative approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing coordination coronary revascularization surgery, in which it is necessary to use the internal saphenous vein as a conduit.

Exclusion Criteria:

* Emergency surgeries.
* Poor metabolic control (HbA1c \> 6.5%).
* Chronic venous insufficiency or chronic obstructive arteriopathy of the lower limbs.
* Type II obesity (BMI\>35).

Where this trial is running

Montevideo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SaphenectomyNo TouchCoronary Artery DiseaseCardiovascular DiseasesWound Complication
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.