Comparing two surgical techniques for treating deep gum defects

Non - Incised Papilla Versus Single Flap Technique In The Reconstruction Of Intrabony Defect: a Randomized Controlled Trial

NA · Ain Shams University · NCT06003322

This study is testing two different surgical methods for fixing deep gum problems to see which one helps people with gum disease feel and heal better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorAin Shams University (other)
Locations1 site (Assiut)
Trial IDNCT06003322 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of the non-Incised Papilla surgical approach (NIPSA) versus the single-flap approach (SFA) in treating deep intraosseous defects associated with periodontal attachment loss. It aims to measure primary outcomes such as interproximal clinical attachment level gain, along with secondary outcomes including probing pocket depth reduction and keratinized tissue width. Participants will undergo surgical debridement using one of the two techniques, and various clinical parameters will be assessed post-operatively to determine the most effective method.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 diagnosed with stage III-IV periodontitis and having specific intrabony defects.

Not a fit: Patients with third molars, teeth with significant mobility, or those with systemic conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes for patients with severe periodontal disease.

How similar studies have performed: Previous studies have shown varying success with different surgical techniques for periodontal treatment, but this specific comparison is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* - Age \> 18 years
* Diagnosis with stage III-IV periodontitis.
* Presence of one or more intrabony defects with probing pocket depth (PPD) \> 5 mm and radiographic defect depth \> 4 mm.
* Full-mouth plaque score (FMPS) and full-mouth bleeding score (FMBS) \< 30% (measured at four sites per tooth).
* No relevant systemic condition or disease.

Exclusion Criteria:

Third molars and teeth with type III mobility or with an incorrect endodontic or restorative treatment.

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Where this trial is running

Assiut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Periodontal Attachment Loss

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.