Comparing two surgical techniques for thymectomy
Video-assisted Thoracoscopic Thymectomy Versus Subxiphoid Thymectomy: Short- Term and Long- Term Results
This study is testing which of two minimally invasive surgical methods for thymectomy works better and is safer for patients with thymoma and generalized myasthenia gravis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | The Second Hospital of Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT04223466 on ClinicalTrials.gov |
What this trial studies
This study compares two minimally invasive surgical techniques for thymectomy: the subxiphoid approach and the conventional video-assisted thoracoscopic surgery (VATS). The aim is to evaluate the effectiveness and safety of these techniques in patients with thymoma and generalized myasthenia gravis. By analyzing outcomes such as recovery time and complication rates, the study seeks to determine which method offers better results for patients. The trial is conducted at The Second Hospital of Shandong University in Jinan, Shandong.
Who should consider this trial
Good fit: Ideal candidates include patients with thymoma or generalized myasthenia gravis who have good cardiopulmonary function.
Not a fit: Patients with compromised cardiopulmonary function or those with MuSK-positive generalized myasthenia gravis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery for patients undergoing thymectomy.
How similar studies have performed: Other studies have shown promising results with minimally invasive approaches in thoracic surgery, suggesting potential success for this comparison.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Thymoma with or without myasthenia gravis； 2. Generalized myasthenia gravis not sensitive to conservative medicine treatment; 3. Good cardiopulmonary function. Exclusion Criteria: 1. Cardiopulmonary function can't bear surgery; 2. Generalized myasthenia gravis with MuSK(+).
Where this trial is running
Jinan, Shandong
- Yunpeng — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Yunpeng Zhao
- Email: zyp_baggio@163.com
- Phone: +8618766188692
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.