Comparing two surgical techniques for thymectomy
Official title: Video-assisted Thoracoscopic Thymectomy Versus Subxiphoid Thymectomy: Short- Term and Long- Term Results
Run by The Second Hospital of Shandong University · NCT04223466 · Data updated 2026-11-12
This study is testing which of two minimally invasive surgical methods for thymectomy works better and is safer for patients with thymoma and generalized myasthenia gravis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 80 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | The Second Hospital of Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Status | Recruiting |
| Started | January 7, 2020 |
| Main results expected | December 31, 2024 |
| Study ends | December 31, 2027 |
| Registry record updated | November 16, 2022 |
| Trial ID | NCT04223466 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with thymoma or generalized myasthenia gravis who have good cardiopulmonary function.
✕Probably not a fit
Patients with compromised cardiopulmonary function or those with MuSK-positive generalized myasthenia gravis may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares two minimally invasive surgical techniques for thymectomy: the subxiphoid approach and the conventional video-assisted thoracoscopic surgery (VATS). The aim is to evaluate the effectiveness and safety of these techniques in patients with thymoma and generalized myasthenia gravis. By analyzing outcomes such as recovery time and complication rates, the study seeks to determine which method offers better results for patients. The trial is conducted at The Second Hospital of Shandong University in Jinan, Shandong.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery for patients undergoing thymectomy.
How similar studies have gone: Other studies have shown promising results with minimally invasive approaches in thoracic surgery, suggesting potential success for this comparison.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Thymoma with or without myasthenia gravis； 2. Generalized myasthenia gravis not sensitive to conservative medicine treatment; 3. Good cardiopulmonary function. Exclusion Criteria: 1. Cardiopulmonary function can't bear surgery; 2. Generalized myasthenia gravis with MuSK(+).
Where it's running
-
Yunpeng
Jinan, Shandong, China Recruiting
Study contacts
- Study coordinator: Yunpeng Zhao
- Email: zyp_baggio@163.com
- Phone: +8618766188692
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Partial versus complete thymus removal during infant heart surgery
This will test whether removing only part of the thymus instead of the whole gland during heart surgery helps preserve immune function in infants under 6 months.
-
Stanford program to advance robotic surgery for children and adolescents
This program will try the da Vinci Xi surgical robot in children and adolescents (ages 6–21, ≥15 kg) to see if it is safe and works well for procedures like sleeve gastrectomy, cholecystectomy, splenectomy, hysterectomy, and operations for endometriosis.
-
Pain management technique for robotic thymectomy
This study is testing a new pain management technique to see if it can help people having robotic thymectomy surgery feel less pain and recover better.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.