Comparing two surgical techniques for managing placenta accreta
Single-step Placenta Accreta Resective Technique Tourniqueted vs Absence, Conservative Uterine Surgery (SPARTACUS) Study
This study is testing if using a tourniquet during surgery helps pregnant women with placenta accreta have safer and better outcomes compared to traditional surgery without it.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | Female |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06185894 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the efficacy and safety of using a tourniquet during conservative surgical management of placenta accreta in pregnant women. It involves 40 participants who have undergone previous cesarean deliveries and meet specific ultrasound criteria for placenta accreta spectrum. The participants are divided into two groups: one receiving the tourniquet intervention and the other receiving conventional surgery without a tourniquet. The goal is to determine if the tourniquet improves outcomes in terms of safety and effectiveness.
Who should consider this trial
Good fit: Ideal candidates are pregnant women with a history of cesarean deliveries and ultrasound-confirmed placenta accreta spectrum who wish to conserve their uterus.
Not a fit: Patients over 40 years old or those with chronic medical conditions or severe antepartum hemorrhage may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to safer surgical options for women with placenta accreta, preserving their fertility.
How similar studies have performed: While there is limited information on similar studies, the approach of using a tourniquet in surgical management is not widely established, making this a potentially novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant females with previous CS deliveries (at least 1). * Patients with ultrasound criteria of placenta accerta spectrum. * Patients desiring fertility (uterine conservation). * Patients with gestational age that completed 34 weeks (or more) confirmed by the 1st day of the LMP or 1st trimester ultrasound scan. Exclusion Criteria: * Maternal age above 40 years. * Chronic medical disorders (e.g., cardiac, renal, DM and hepatic diseases). * Patients presented with severe antepartum hemorrhage (unstable vital signs). * Patients requested radical management (caesarean hysterectomy).
Where this trial is running
Cairo
- Cairo University — Cairo, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.