Comparing two surgical techniques for knee replacement
Comparison of Functional Outcomes in Restricted Kinematic Alignment and Mechanical Alignment in Robotic Assisted Simultaneous Bilateral Total Knee Arthroplasty. A Randomized Controlled Trial
This study tests whether a new knee surgery technique can help people with osteoarthritis feel less pain and move better compared to a standard method.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Thammasat University Hospital Academic / other |
| Locations | 1 site (Khlong Luang, Changwat Pathum Thani) |
| Trial ID | NCT06323577 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the efficacy of restricted kinematic alignment (rKA) versus mechanical alignment (MA) in patients undergoing simultaneous bilateral total knee arthroplasty (TKA) due to osteoarthritis. Participants will be randomly assigned to receive one technique on one knee and the other technique on the opposite knee. The study aims to determine if rKA leads to better functional outcomes and lower pain scores compared to MA in this patient population.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40-80 with bilateral primary osteoarthritis of the knee who are scheduled for simultaneous bilateral TKA.
Not a fit: Patients with a BMI over 40, a history of previous knee surgery, or active knee joint infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and pain management for patients undergoing knee replacement surgery.
How similar studies have performed: Other studies have explored similar alignment techniques in knee surgery, showing promising results, but this specific comparison is less common.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 40-80 years * Diagnosis bilateral primary osteoarthritis of knee joint and undergo simultaneous bilateral total knee arthroplasty * ASA classification I-II Exclusion Criteria: * Valgus deformity * BMI \> 40kg/m2 * History of previous knee surgery * Active infection of the knee joint
Where this trial is running
Khlong Luang, Changwat Pathum Thani
- Thammasat University — Khlong Luang, Changwat Pathum Thani, Thailand (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.