Comparing two surgical techniques for colorectal cancer

Comparative Study Between End to End Anastomosis With Omega Suture Versus End to Anterior Rectal Wall In Colorectal Anastomosis in Sigmoid and Upper Rectal Cancer

Not applicable Interventional Ain Shams University · NCT06546176

This study is testing two different surgical methods for connecting parts of the colon after cancer surgery to see which one leads to fewer complications and better recovery for patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06546176 on ClinicalTrials.gov

What this trial studies

This study aims to compare two surgical techniques for colorectal anastomosis in patients with sigmoid and upper rectal cancer. It evaluates the end to end anastomosis with omega suture against the end to anterior rectal wall approach, focusing on postoperative outcomes such as anastomotic leakage, bowel function, operative time, and intraoperative blood loss. The research seeks to establish which technique provides better safety and effectiveness in preventing complications associated with colorectal surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with recto-sigmoidal carcinoma or upper rectal cancer.

Not a fit: Patients with recurrent or non-resectable cancer, complicated cancer, or those who have had previous left-sided colorectal or anorectal surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients undergoing surgery for colorectal cancer.

How similar studies have performed: While there have been studies on various anastomotic techniques, this specific comparison of omega suture versus anterior rectal wall is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged \>18 years.
* Both sexes.
* Recto sigmoidal carcinoma.
* Upper rectal cancer.

Exclusion Criteria:

* Patients younger than 18 years
* Recurrent or non-resectable cancer
* Complicated cancer (e.g., obstructed or perforated)
* Previous left-sided colorectal surgery or anorectal surgeries
* Lower rectal cancer

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions End to End AnastomosisColorectal AnastomosisEnd to Anterior Rectal WallSigmoid CancerUpper Rectal Cancer
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.