Comparing two surgical options for wrist osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the outcomes of proximal row carpectomy (PRC) versus four-corner fusion (FCA) in patients with SLAC/SNAC II-III type osteoarthritis of the wrist. Patients with confirmed osteoarthritis will be randomly assigned to one of the two surgical procedures in a double-blinded manner. Data will be collected preoperatively and during follow-up visits at various intervals up to 10 years post-surgery to assess the effectiveness of each intervention. The allocation of treatment will remain concealed until the 12-month follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* SLAC/SNAC II-III
* Age 18 - 75
* Symptom duration \> 3 months
* American Society of Anaesthesiologists physical status (ASA) I-II

Exclusion Criteria:

* Patient eligible for SL reconstruction or scaphoid
* Ulnocarpal/pancarpal arthritis
* Lunate fossa, proximal lunate arthrosis or both
* Age \<18 or \>75 years
* Rheumatoid arthritis
* Heavy smoking (\> 20 cigarettes per day)
* Condition or medication affecting bony healing (eg diabetes mellitus with poor glycemic control, malnutrition, use of per oral corticosteroids)
* Alcohol or drug abuse
* Neurological condition affecting upper limb function

Where it's running

• Töölö Hospital (Helsinki University Hospital)
  Helsinki, Finland Recruiting
• Central Hospital of Central Finland
  Jyväskylä, Finland Not yet recruiting
• Kymenlaakso Central Hospital
  Kotka, Finland Not yet recruiting
• Tampere University Hospital
  Tampere, Finland Not yet recruiting
• Turku University Hospital
  Turku, Finland Not yet recruiting

Study contacts

• Study coordinator: Samuli Aspinen, MD, PhD
• Email: samuli.aspinen@hus.fi
• Phone: +358406360546

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Web-based rehab after wrist salvage surgery

  A web-based rehabilitation program is tested to see if it works as well as standard in-person rehab after wrist salvage surgery for osteoarthritis.

  Recruiting Karolinska Institutet · Stockholm · NCT06814821

• Using tissue grafts to treat wrist osteoarthritis

  This study is testing a new surgery using tissue grafts to see if it can help people with wrist osteoarthritis feel better and recover more effectively than using synthetic materials.

  Recruiting University of Colorado, Denver · Englewood, Colorado · NCT05412615

• Comparing two techniques for wrist fusion in patients with post-traumatic arthritis

  This study is testing two different surgery techniques for wrist fusion to see which one helps adults with post-traumatic arthritis feel better and regain more movement in their wrists.

  Recruiting at 5 sites University of Alberta · Calgary, Alberta and 4 other locations · NCT04580225

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.