Comparing two surgical methods for treating syringomyelia
Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia
NA · Xuanwu Hospital, Beijing · NCT06375759
This study is testing which surgical method works better for people with syringomyelia and spinal arachnoiditis: a bypass surgery or a procedure to break up adhesions.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Xuanwu Hospital, Beijing (other) |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06375759 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of Subarachnoid-Subarachnoid (S-S) Bypass compared to intradural adhesion lysis in patients suffering from spinal arachnoiditis and syringomyelia. Participants will be randomly assigned to one of the two surgical interventions and will undergo follow-up assessments at 3-6 months, 12 months, and 24 months post-surgery. These assessments will include physical examinations, symptom reporting, and MRI scans to monitor changes in their condition. The goal is to determine which method leads to better outcomes and fewer complications.
Who should consider this trial
Good fit: Ideal candidates are individuals with a history of traumatic spinal cord injury or infection, showing progressive neurological deficits or pain, and confirmed syringomyelia via MRI.
Not a fit: Patients with Chiari malformation, myelomalacia, subarachnoid cysts, or syringomyelia due to other spinal diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical options and quality of life for patients with syringomyelia.
How similar studies have performed: There is limited information on the success of similar approaches, making this study a potentially novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\) history of traumatic spinal cord injury or other infection; 2) evidence of progressive neurological deficit, and/or pain syndrome; 3) MRI showing a syringomyelia due to spinal trauma or other infection; and 4) minimum follow-up period of more than 1 year. Exclusion Criteria: * Chiari-malformation, myelomalacia, subarachnoid cyst, syringomyelia due to other spinal diseases (such as degenerative spinal disease)
Where this trial is running
Beijing, Beijing Municipality
- Fengzeng Jian — Beijing, Beijing Municipality, China (RECRUITING)
Study contacts
- Study coordinator: fengzeng jian
- Email: jianfengzeng@xwh.ccmu.edu.cn
- Phone: 01083198899
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Syringomyelia, syringomyelia