Comparing two surgical methods for treating severe hemorrhoids

A Randomized Prospective Clinical Trial Comparing the Surgical Outcomes of Traditional Ferguson Hemorrhoidectomy Versus Stapled Hemorrhoidopexy With Anoplasty for Patients With Grade III/IV Hemorrhoids

NA · National Taiwan University Hospital · NCT05959577

This study is testing whether a newer surgical method for treating severe hemorrhoids works better and causes fewer problems than the traditional surgery for people with serious symptoms.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages25 Years to 75 Years
SexAll
SponsorNational Taiwan University Hospital (other)
Locations1 site (Taipei)
Trial IDNCT05959577 on ClinicalTrials.gov

What this trial studies

This study compares the outcomes of stapled hemorrhoidopexy with anoplasty to the traditional Ferguson hemorrhoidectomy for patients suffering from grade III and IV hemorrhoids. The research aims to evaluate both short- and long-term results of these surgical techniques, which are commonly used to address severe hemorrhoidal disease. Given the prevalence of hemorrhoids in the general population, this study seeks to determine which method provides better relief and fewer complications for patients. The study will include patients aged 25 to 75 who have severe symptoms and meet specific health criteria.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 25 to 75 with grade III or IV hemorrhoids experiencing severe symptoms.

Not a fit: Patients with severe liver cirrhosis, chronic renal disease, or coagulopathy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for patients with severe hemorrhoids.

How similar studies have performed: Previous studies have shown varying results with similar surgical approaches, indicating a need for further investigation in this area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged between 25\~75 years with subjective, severe hemorrhoidal symptoms
* Graded III-IV hemorrhoid
* The patients' condition can undergo hemorrhoidectomy
* ASA status ≤ 3

Exclusion Criteria:

* Severe liver cirrhosis
* Chronic renal disease
* Coagulopathy

Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Haemorrhoid, Hemorrhoid, Ferguson hemorrhoidectomy, Stapled hemorrhoidopexy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.