Comparing two surgical methods for treating gastric cancer
Official title: Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer
Run by Nanchong Central Hospital · NCT05514769 · Data updated 2026-11-12
This study tests which of two surgical methods works better for people with gastric cancer to improve their recovery and quality of life after surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Nanchong Central Hospital Government |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Nanchong, Sichuan) |
| Status | Recruiting |
| Started | January 1, 2021 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | March 31, 2026 |
| Trial ID | NCT05514769 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with histologically confirmed adenocarcinoma of the stomach at T1-T4 stages and a performance status of 0 or 1.
✕Probably not a fit
Patients with distant metastasis, significant esophageal invasion, or those who have received prior chemotherapy or radiation therapy for other malignancies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare two surgical techniques for patients with proximal gastric adenocarcinoma: proximal gastrectomy with anterior anastomosis and pyloroplasty versus esophagogastric anastomosis. The research will evaluate postoperative quality of life, short-term outcomes, and long-term outcomes associated with each surgical approach. By analyzing these factors, the study seeks to determine which method may provide better results for patients undergoing surgery for gastric cancer.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for patients with gastric cancer.
How similar studies have gone: While this specific comparison may be novel, similar surgical approaches have shown varying degrees of success in treating gastric cancer in other studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages. 2. Eastern Cooperative Oncology Group performance status of 0 or 1. 3. Adequate organ function. Exclusion Criteria: 1. Patients had distant metastasis. 2. oesophageal invasion of more than 3 cm. 3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma. 4. Previous chemotherapy or radiation therapy for any other malignancies.
Where it's running
-
Yunhong Tian
Nanchong, Sichuan, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.