Clinical trial Recruiting at 1 site Interventional Ages 18 to 85

Comparing two surgical methods for treating gastric cancer

Official title: Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer

Run by Nanchong Central Hospital · NCT05514769 · Data updated 2026-11-12

This study tests which of two surgical methods works better for people with gastric cancer to improve their recovery and quality of life after surgery.

Quick facts

Study typeInterventional
Ages18 Years to 85 Years
SexAll
Enrollment60 (estimated)
SponsorNanchong Central Hospital
Government
Drugs / interventionschemotherapy, radiation
Locations1 site (Nanchong, Sichuan)
StatusRecruiting
StartedJanuary 1, 2021
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedMarch 31, 2026
Trial IDNCT05514769 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals with histologically confirmed adenocarcinoma of the stomach at T1-T4 stages and a performance status of 0 or 1.

Probably not a fit

Patients with distant metastasis, significant esophageal invasion, or those who have received prior chemotherapy or radiation therapy for other malignancies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare two surgical techniques for patients with proximal gastric adenocarcinoma: proximal gastrectomy with anterior anastomosis and pyloroplasty versus esophagogastric anastomosis. The research will evaluate postoperative quality of life, short-term outcomes, and long-term outcomes associated with each surgical approach. By analyzing these factors, the study seeks to determine which method may provide better results for patients undergoing surgery for gastric cancer.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for patients with gastric cancer.

How similar studies have gone: While this specific comparison may be novel, similar surgical approaches have shown varying degrees of success in treating gastric cancer in other studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages.
2. Eastern Cooperative Oncology Group performance status of 0 or 1.
3. Adequate organ function.

Exclusion Criteria:

1. Patients had distant metastasis.
2. oesophageal invasion of more than 3 cm.
3. Borrmann type 4 or large (more than 8 cm) type 3 carcinoma.
4. Previous chemotherapy or radiation therapy for any other malignancies.

Where it's running

  • Yunhong Tian
    Nanchong, Sichuan, China
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.