Comparing two surgical methods for treating enlarged prostate

Bipolar Trans Urethral Resection of the Prostate (TURP) Versus Bipolar Enucleation of the Prostate in Treatment of Benign Prostatic Hyperplasia (BPH): A Prospective Randomized Comparative Clinical Study

This study is testing two different surgical methods for treating an enlarged prostate to see which one is safer and more effective for men with urinary problems.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 100 (estimated)
• Ages: 50 Years to 80 Years
• Sex: Male
• Sponsor: South Valley University (other)
• Locations: 1 site (Qina, Qena Governorate)
• Trial ID: NCT06983444 on ClinicalTrials.gov

What this trial studies

This study evaluates the efficacy and safety of two surgical techniques for managing benign prostatic hyperplasia (BPH): transurethral resection of the prostate (TURP) and bipolar enucleation of the prostate (TUEP). TURP has been the traditional gold standard but carries significant risks and complications, while TUEP is a minimally invasive alternative that may offer similar effectiveness with fewer complications. The study aims to compare these two approaches to determine their true benefits and safety profiles. Patients with lower urinary tract symptoms due to BPH will be enrolled based on specific eligibility criteria.

Who should consider this trial

Good fit: Ideal candidates are men aged 50-80 with lower urinary tract symptoms due to BPH and specific urinary flow rate and prostate volume criteria.

Not a fit: Patients with prostate or bladder cancer, urethral stricture, or neurogenic bladder may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a safer and more effective surgical option for patients suffering from BPH.

How similar studies have performed: Previous studies have shown promising results for minimally invasive approaches like bipolar enucleation, indicating potential success for this comparison.

Eligibility criteria

Inclusion Criteria:

1. Patients with lower urinary tract symptoms (LUTS) due to BPH.
2. Patients with international prostate score system (IPSS) more than 8.
3. Patients with maximal urinary flow rate (Qmax) less than 10ml/second.
4. Patients with Prostatic volume (60 - 100 gm).
5. Patient with indication for surgical intervention.
6. Patient age (50-80 years old)

Exclusion Criteria:

1. Prostatic cancer.
2. Bladder cancer.
3. Urethral stricture.
4. Neurogenic bladder.

Where this trial is running

Qina, Qena Governorate

• Faculty of Medicine South Valley University — Qina, Qena Governorate, Egypt (RECRUITING)

Study contacts

• Study coordinator: AHMED A.FATAH HAMED, Master's

Conditions: Benign Prostatic Hyperplasia Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction, Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms, TURP, TUEP, BPH