Comparing two surgical methods for rectal endometriosis
A Retrospective Single-center Cohort Study on the Prognosis of Disc Resection and Segmental Resection Followed by Anastomosis on Gastrointestinal Function and Quality of Life in Patients With Rectal Endometriosis
This study looks at two different surgical methods for treating rectal endometriosis to see which one helps patients recover better and have more successful pregnancies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Fudan University Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT06254716 on ClinicalTrials.gov |
What this trial studies
This observational study aims to retrospectively compare the surgical and pregnancy outcomes of two surgical methods, disc resection and segmental resection, in patients with rectal endometriosis. By analyzing clinical data from a single center, the study will evaluate perioperative complications, disease relief, and recurrence rates associated with each surgical approach. Additionally, it will follow up on fertility outcomes for patients desiring pregnancy, providing a clinical basis for future prospective studies.
Who should consider this trial
Good fit: Ideal candidates include patients who have undergone surgery for rectal endometriosis involving the rectal mucosa or submucosa.
Not a fit: Patients who have previously undergone surgical treatment for rectal endometriosis or those with malignant tumors will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help determine the most effective surgical method for improving gastrointestinal function and pregnancy outcomes in patients with rectal endometriosis.
How similar studies have performed: While this study focuses on a specific comparison of surgical methods, similar studies have shown success in evaluating surgical outcomes for endometriosis, suggesting potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent surgery of disc and segmental resection followed by anastomosis for endometriosis * Endometriosis involving the full thickness of the rectum reaching the mucosa or submucosa during preoperative evaluation or intraoperative exploration, and who were diagnosed pathologically. Exclusion Criteria: * Patients who have previously undergone surgical treatment of rectal endometriosis * Patients with insufficient preoperative evaluation (lack of pelvic imaging evaluation or colonoscopy evaluation) and surgical removal of lesions; * Postoperative pathology shows rectal mucosa or The submucosa is not involved; patients with malignant tumors.
Where this trial is running
Shanghai, Shanghai
- OB & GYN Hospital of Fudan University — Shanghai, Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Hexia Xia, M.D.
- Email: hexia_xia@fudan.edu.cn
- Phone: +8613601843476
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.