Clinical trial No longer in our active list Observational Ages 18 to 90

Comparing two surgical methods for gastric cancer treatment

Official title: Comparative Analysis of Short-Term Therapeutic Effects Between the π-Shaped and Overlap Methods for Esophagogastrostomy in Totally Laparoscopic Total Gastrectomy

Run by Northern Jiangsu People's Hospital · NCT06383793 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing which of two surgical methods for treating gastric cancer helps patients recover better and feel safer after surgery.

Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexAll
Enrollment100 (estimated)
SponsorNorthern Jiangsu People's Hospital
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Yangzhou, Jiangsu)
Trial IDNCT06383793 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients diagnosed with adenocarcinoma of the upper stomach who are undergoing total laparoscopic total gastrectomy.

Probably not a fit

Patients with severe preoperative complications or those who have undergone previous abdominal surgeries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the short-term therapeutic effects and safety of two surgical techniques, the π-shaped anastomosis and the overlap method, used during laparoscopic total gastrectomy for gastric cancer. By analyzing outcomes from patients who underwent these procedures, the research aims to provide valuable insights for surgeons in selecting the most effective anastomotic technique. The study focuses on patients with adenocarcinoma located in the upper parts of the stomach, utilizing observational methods to gather data on surgical effectiveness and patient recovery.

Why it matters

Potential benefit: If successful, this study could help improve surgical outcomes and recovery for patients undergoing total gastrectomy for gastric cancer.

How similar studies have gone: While there have been discussions on the safety of these methods, direct comparative studies like this one are limited, making this approach relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:(1) preoperative confirmation through electronic gastroscopy and enhanced CT that the lesion was situated in the fundus, middle and upper third of the gastric body, or the entire stomach; (2) postoperative pathology confirming adenocarcinoma; (3) utilization of either overlap esophagojejunal anastomosis or π-shaped anastomosis in total laparoscopic total gastrectomy.

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Exclusion Criteria:(1) patients with severe preoperative cardiac, hepatic, renal, and pulmonary complications; (2) preoperative neoadjuvant chemotherapy; (3) a history of previous abdominal surgery; (4) patients requiring combined resection due to infiltration of other organs during the operation; (5) patients with incomplete pathological or clinical data. All patients signed informed consent.

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Where it's running

  • Yifan Cheng
    Yangzhou, Jiangsu, China
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.