Comparing two surgical methods for gastric cancer treatment
Comparative Analysis of Short-Term Therapeutic Effects Between the π-Shaped and Overlap Methods for Esophagogastrostomy in Totally Laparoscopic Total Gastrectomy
Northern Jiangsu People's Hospital · NCT06383793
This study is testing which of two surgical methods for treating gastric cancer helps patients recover better and feel safer after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Northern Jiangsu People's Hospital (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Yangzhou, Jiangsu) |
| Trial ID | NCT06383793 on ClinicalTrials.gov |
What this trial studies
This study compares the short-term therapeutic effects and safety of two surgical techniques, the π-shaped anastomosis and the overlap method, used during laparoscopic total gastrectomy for gastric cancer. By analyzing outcomes from patients who underwent these procedures, the research aims to provide valuable insights for surgeons in selecting the most effective anastomotic technique. The study focuses on patients with adenocarcinoma located in the upper parts of the stomach, utilizing observational methods to gather data on surgical effectiveness and patient recovery.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with adenocarcinoma of the upper stomach who are undergoing total laparoscopic total gastrectomy.
Not a fit: Patients with severe preoperative complications or those who have undergone previous abdominal surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help improve surgical outcomes and recovery for patients undergoing total gastrectomy for gastric cancer.
How similar studies have performed: While there have been discussions on the safety of these methods, direct comparative studies like this one are limited, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:(1) preoperative confirmation through electronic gastroscopy and enhanced CT that the lesion was situated in the fundus, middle and upper third of the gastric body, or the entire stomach; (2) postoperative pathology confirming adenocarcinoma; (3) utilization of either overlap esophagojejunal anastomosis or π-shaped anastomosis in total laparoscopic total gastrectomy. - Exclusion Criteria:(1) patients with severe preoperative cardiac, hepatic, renal, and pulmonary complications; (2) preoperative neoadjuvant chemotherapy; (3) a history of previous abdominal surgery; (4) patients requiring combined resection due to infiltration of other organs during the operation; (5) patients with incomplete pathological or clinical data. All patients signed informed consent. -
Where this trial is running
Yangzhou, Jiangsu
- Yifan Cheng — Yangzhou, Jiangsu, China (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastric Cancer