Comparing two sedation methods for gastrointestinal endoscopy
Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation During Gastrointestinal Endoscopy
NA · Sohag University · NCT06756594
This study is testing which sedation method, Dexmedetomidine-Propofol or Ketamine-Propofol, works better for people having gastrointestinal endoscopy by looking at how stable their vital signs are and if they experience fewer side effects afterward.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06756594 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of two sedation combinations, Dexmedetomidine-Propofol and Ketamine-Propofol, during upper or lower gastrointestinal endoscopy procedures. The focus is on evaluating hemodynamic stability and the incidence of postoperative side effects such as delirium, nausea, vomiting, headache, hallucination, or agitation. By assessing these factors, the study aims to determine which sedation method provides better outcomes for patients undergoing these procedures.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18 to 60 with an American Society of Anesthesiologists physical status of I to II.
Not a fit: Patients with severe heart, lung, liver disease, kidney failure, or other significant health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved sedation practices, enhancing patient comfort and safety during gastrointestinal endoscopy.
How similar studies have performed: While there have been studies comparing sedation methods, this specific combination approach is relatively novel and may provide new insights into sedation efficacy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists physical status I to II. * Age between 18 and 60 years. * Both sexes. Exclusion Criteria: * Having severe heart, lung, liver disease, kidney failure, or bleeding disorder. * Patients having fever, hypothermia or infection, electrolyte disorders, such as hypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.
Where this trial is running
Sohag
- Sohag University Hospital — Sohag, Egypt (RECRUITING)
Study contacts
- Study coordinator: Ahmed H Hamed, Resident
- Email: Ahmedh9996@yahoo.com
- Phone: 01124623298
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Propofol