Comparing two pain relief methods for kidney surgery

Analgesic Efficacy of External Oblique Intercostal Block Versus Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy

NA · Cairo University · NCT06584695

This study is testing which of two pain relief methods works better for cancer patients undergoing kidney surgery to help them feel less pain and be happier with their care.

Quick facts

PhaseNA
Study typeInterventional
Enrollment63 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorCairo University (other)
Locations1 site (Cairo)
Trial IDNCT06584695 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of two regional anesthesia techniques, the external oblique intercostal block and the subcostal transversus abdominis plane block, in providing pain relief during and after open nephrectomy in cancer patients. The research will utilize ultrasound guidance to administer these blocks and assess their impact on opioid requirements and patient satisfaction. Given the high incidence of postoperative pain associated with nephrectomy, this study seeks to establish a more effective analgesic approach to improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are cancer patients aged 18-65 who are scheduled for open nephrectomy and classified as ASA class II or III.

Not a fit: Patients with ASA class IV, significant cognitive or psychiatric disorders, or those with a BMI over 35 may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing open nephrectomy, reducing opioid use and enhancing recovery.

How similar studies have performed: Previous studies have shown that ultrasound-guided regional anesthesia techniques can effectively reduce pain and opioid requirements in similar surgical settings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age (18-65) year.
* Both sexes.
* American Society of Anesthesiologists (ASA) class II and III.
* Cancer patients candidate for open nephrectomy .

Exclusion Criteria:

* Patient refusal.
* Skin lesions or infection at the site of proposed needle insertion.
* Cognitive disorders.
* History of psychiatric disorders or drug abuse.
* Patients allergic to medication used.
* ASA class IV.
* Coagulopathy.
* Body mass index (BMI) more than 35.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Analgesic Efficacy, External Oblique Intercostal Block, Subcostal Transversus Abdominis Plane Block, Open, Nephrectomy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.