Comparing two pain relief methods after laparoscopic appendectomy
Ultrasound-guided Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia of Adult Patients Undergoing Laparoscopic Appendectomy
This study is testing which of two pain relief methods works better for people aged 18-50 after having their appendix removed using a minimally invasive surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06220513 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness and safety of two ultrasound-guided nerve blocks, the erector spinae plane block and the transversus abdominis plane block, for managing postoperative pain in patients undergoing laparoscopic appendectomy. The goal is to determine which method provides better analgesia and reduces the need for additional pain medication. Patients aged 18-50 with ASA physical status I or II will be included, while those with certain medical conditions or contraindications will be excluded. The study is conducted at Ain Shams University hospitals in Cairo.
Who should consider this trial
Good fit: Ideal candidates are patients aged 18-50 scheduled for laparoscopic appendectomy with ASA physical status I or II.
Not a fit: Patients with allergies to local anesthetics, significant comorbidities, or those who require conversion to open surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic appendectomy, enhancing recovery and reducing hospital stays.
How similar studies have performed: Previous studies have shown that ultrasound-guided nerve blocks can effectively reduce postoperative pain, suggesting that this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for laparoscopic appendectomy, * Patients aged 18-50 years, * American Society of Anaesthesiologists (ASA) physical status I or II. Exclusion Criteria: * Declined informed consent. * Allergy to local anesthetics. * Conversion of the laparoscopic surgery to open appendectomy. * Coagulation disorder. * Pregnancy, * BMI more than 40 kg/m2, * Respiratory disease, liver or kidney disease; and heart disease (heart block, Rheumatic heart or myocardial ischemia). * Psychiatric problems, that results in lack of communication ability. * Chronic alcoholism, drug abuse, * Infection in the area where the block will be applied.
Where this trial is running
Cairo
- Ain shams university hospitals — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Eman Abdelnaby, master
- Email: Eman_soliman@med.asu.edu.eg
- Phone: 01094675379
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.