Comparing two pain relief methods after breast cancer surgery
Ultrasound-guided Thoracic Interfascial Plane Nerve Block Versus Erector Spinae Plane Block for Postoperative Pain Control in Patients Undergoing Modified Radical Mastectomy
This study is testing which of two pain relief methods works better for women after breast cancer surgery to help them feel less pain and be more satisfied with their recovery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 21 Years and up |
| Sex | Female |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo, Abbasiya) |
| Trial ID | NCT06548646 on ClinicalTrials.gov |
What this trial studies
This clinical trial compares the effectiveness of two ultrasound-guided nerve blocks, the Thoracic Interfascial Plane Block (TIPB) and the Erector Spinae Plane Block (ESPB), for managing postoperative pain in women undergoing Modified Radical Mastectomy for breast cancer. Participants will be randomly assigned to receive one of the two nerve blocks before surgery, with pain levels assessed postoperatively using the Visual Analog Scale (VAS). The study aims to determine which technique provides better pain relief, reduces the need for rescue medication, and enhances overall patient satisfaction.
Who should consider this trial
Good fit: Ideal candidates are women aged 21 and older scheduled for a Modified Radical Mastectomy at Ain Shams University hospitals.
Not a fit: Patients with significant organ dysfunction, coagulopathy, or those with known allergies to the study medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies that minimize opioid use and enhance recovery for patients undergoing breast cancer surgery.
How similar studies have performed: Previous studies have shown promising results with similar nerve block techniques for postoperative pain management, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female patients older than 21 years old * American Society of Anesthesiologists (ASA) physical status II. Exclusion Criteria: * Known allergy to one of the study\'s medications. * Skin infections at the site of the needle puncture. * Significant organ dysfunction (hepatic, renal, or cardiac dysfunction), coagulopathy or recent anticoagulant use, epilepsy. * Patients diagnosed with obstructive sleep apnoea, pulmonary compromise .
Where this trial is running
Cairo, Abbasiya
- Ainshams University Hospitals — Cairo, Abbasiya, Egypt (Recruiting)
Study contacts
- Study coordinator: Safie R Abd El Moneim, Masters
- Email: safie.ramez@med.asu.edu.eg
- Phone: 01280202299
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.