Comparing two pain management techniques for knee surgery

Comparison of Efficacy Between Ultra-sound Genicular Nerve Block Versus the Popliteal Artery and the Capsule of the Posterior Knee(IPACK) Block for Knee Arthroscopic Surgery

Not applicable Interventional Assiut University · NCT05561881

This study is testing whether two different pain relief methods after knee surgery can help patients feel better and recover faster while using less opioid medication.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorAssiut University Academic / other
Locations1 site (Assiut)
Trial IDNCT05561881 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of genicular nerve blocks versus IPACK blocks for managing postoperative pain in patients undergoing knee arthroscopic surgery. It aims to improve patient satisfaction and clinical outcomes while reducing opioid use through better pain management strategies. The genicular nerve block targets specific nerves that innervate the knee joint, while the IPACK block focuses on providing analgesia to the posterior knee joint. Both techniques are assessed for their impact on recovery and rehabilitation following surgery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 20 to 60 years, classified as American Society of Anesthesiologists class I-III, with a BMI of 18-35, scheduled for primary unilateral knee arthroscopic surgery.

Not a fit: Patients with known allergies to local anesthesia, contraindications to local anesthesia injection, or preexisting motor or sensory deficits in the lower extremities may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing knee arthroscopic surgery, enhancing recovery and reducing reliance on opioids.

How similar studies have performed: Previous studies have shown promising outcomes with both genicular and IPACK blocks in similar surgical contexts, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age 20_60 years
* American Society of anthologist class I-III
* BMI18_35 kg/m2
* scheduled for primary unilateral knee arthroscopic surgery

Exclusion Criteria:

* known allergy to local anesthesia
* contraindication to local anesthesia injection (e.g., infection at the site of injection
* contraindication to spinal anesthesia (e.g., coagulopathy)
* patients with preexisting motor or sensory deficit in lower extremities
* insulin or non-insulin-dependent diabetes mellitus
* systemic corticosteroids use within 30 days
* history of arrhythmia or seizures
* severe renal insufficiency
* patient refusal

Where this trial is running

Assiut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Genicular Nerve Block
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.