Comparing two pain management techniques for abdominal hysterectomy

Comparison of the Analgesic Effect of Intrathecal Morphine and Bilateral Transversus Abdominis Plane Block in Patients Undergoing Elective Abdominal Hysterectomy

NA · Ataturk Training and Research Hospital · NCT06815393

This study tests which pain management method works better for women after abdominal hysterectomy to help them recover with less reliance on opioids.

Quick facts

PhaseNA
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorAtaturk Training and Research Hospital (other)
Locations1 site (Erzurum, Yakutiye)
Trial IDNCT06815393 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of two different analgesia techniques, intratechal morphine and transversalis fascia plane block, in managing postoperative pain for women undergoing abdominal hysterectomy. The goal is to optimize pain management and reduce the need for systemic opioids, thereby minimizing opioid-related side effects. By utilizing multimodal analgesia, the study aims to enhance recovery and improve patient outcomes following surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 to 65 years classified as ASA 1 and ASA 2.

Not a fit: Patients with severe comorbidities, allergies to the study medications, or those unable to use the PCA device may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for women undergoing abdominal hysterectomy, enhancing their recovery experience.

How similar studies have performed: Previous studies have shown promising results with multimodal analgesia approaches, indicating potential success for this comparative analysis.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women aged between 18 and 65 years classified as ASA 1 and ASA 2.

Exclusion Criteria:

* Patients with allergies to the active substance, those with severe liver or renal insufficiency, a history of long-term nonsteroidal anti-inflammatory drug (NSAID) and opioid analgesic use, a history of gastrointestinal bleeding, peptic ulcer or inflammatory bowel disease, a history of diabetes or other neuropathic conditions, preoperative atrioventricular block and bradycardia, underlying serious respiratory diseases, a history of psychiatric disorders, patients classified as ASA stage 3 or higher, patients weighing less than 40 kg, patients unable to use the patient-controlled analgesia (PCA) device, and patients who need to discontinue the study medication during surgery for any reason will be excluded from the study

Where this trial is running

Erzurum, Yakutiye

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Abdominal Hysterectomy, abdominal hysterectomy, intratechal morphine, transversalis fascia plane block

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.