Comparing two pain management techniques after mastectomy

Comparison Between Ultrasound Guided Erector Spinae Plane Block and Paravertebral Block on Acute and Chronic Postmastectomy Pain

NA · South Egypt Cancer Institute · NCT04498234

This study tests which pain management technique, ultrasound-guided erector spinae plane block or paravertebral block, works better for people recovering from mastectomy surgery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment108 (estimated)
Ages20 Years to 70 Years
SexFemale
SponsorSouth Egypt Cancer Institute (other)
Locations1 site (Assiut)
Trial IDNCT04498234 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of ultrasound-guided erector spinae plane block and paravertebral block in managing acute and chronic pain following mastectomy. It aims to determine which technique provides better postoperative analgesia for patients undergoing this surgery. The study involves administering local anesthetic solutions to assess pain relief outcomes. By evaluating the incidence of postsurgical pain syndrome, the research seeks to enhance pain management strategies for breast surgery patients.

Who should consider this trial

Good fit: Ideal candidates for this study are females aged 20 to 70 scheduled for a modified radical mastectomy with ASA physical status I or II.

Not a fit: Patients with ASA physical status greater than III, those over 70 years old, or with certain medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management techniques for patients undergoing mastectomy, reducing the incidence of chronic pain.

How similar studies have performed: Previous studies have shown that regional analgesia techniques can effectively reduce postoperative pain, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Gender : female .
2. Age : 20 to 70 years old .
3. Scheduled for : either left or right modified radical mastectomy (MRM)
4. Physical status : American society of anesthesiologists (ASA) physical status I and II.

Exclusion Criteria:

1-ASA \> III 2 -age\> 70 years old. 3-patients refusal to the procedure. 4-Infection of the skin at or near site of needle puncture. 5- Coagulopathy . 6- Drug hypersensitivity or allergy to the studied drugs. 7- Central or peripheral neuropthy . 8-Pre-operative opoid consumption ( within 24 hours preoperative ) 9- Anomalies of the vertebral column .

Where this trial is running

Assiut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Comparison Between Ultrasound Guided Erector Spinae Plane Block and Para-vertebral Block on Acute and Chronic Post Mastectomy Pain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.