Comparing two pain management techniques after lung surgery
Official title: Paravertebral Block or Serratus Posterior Superior Intercostal Plane Block in Pain Management After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Clinical Trial
Run by Koç University · NCT06426706 · Data updated 2026-11-12
This study tests which of two pain management techniques works better for people having lung surgery to help them feel less pain and have fewer side effects afterward.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 44 (estimated) |
| Sponsor | Koç University Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | January 3, 2025 |
| Main results expected | February 15, 2025 |
| Study ends | March 15, 2025 |
| Registry record updated | January 3, 2025 |
| Trial ID | NCT06426706 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-80 who are scheduled for video-assisted thoracoscopic surgery.
✕Probably not a fit
Patients with allergies to local anesthetics, chronic opioid use, or psychiatric disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare the effectiveness of two regional anesthesia techniques, thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB), in managing postoperative pain for patients undergoing video-assisted thoracoscopic surgery (VATS). Participants will be randomly assigned to receive either TPVB or SPSIPB before their surgery. The study will evaluate total opioid consumption, pain scores, and opioid-related side effects in the 24 hours following the procedure. The goal is to determine which technique provides better pain relief and fewer side effects.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing lung surgery, reducing opioid consumption and associated side effects.
How similar studies have gone: Previous studies have shown varying success with regional anesthesia techniques, but this specific comparison of TPVB and SPSIPB is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients between the age of 18-80 undergoing video-assisted thoracoscopic surgery Exclusion Criteria: * Allergy to local anaesthetics Chronic opioid use history Patients with psychiatric disorders Patients who are not open to communication Patients with chronic organ failure Patients that do not give consent Patients that need emergency surgery within the first 24 hours of the initial surgery
Where it's running
-
Koc University
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Kamil Darçın, MD — Koç University
- Study coordinator: Kamil Darçın, MD
- Email: drdarcink@gmail.com
- Phone: +90 505 589 50 99
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Transdermal buprenorphine patch added to multimodal pain relief after VATS
This study tests whether adding a 5 mcg/hour buprenorphine patch to standard pain relief after unilateral VATS reduces pain in adults.
-
Ketamine or Dexmedetomidine as an Additive to Scalp Block for Brain Tumor Surgery
This trial tests whether adding ketamine or dexmedetomidine to bupivacaine for scalp blocks improves pain control after supratentorial brain tumor removal.
-
Impact of Communication Delays on Anesthesia Response in Medical Emergencies and Ultrasound-Guided Nerve Blocks
This study tests how an 80-second communication delay affects the speed and quality of regional anesthesia nerve blocks during emergencies in a spaceflight-like setting.
-
Rhomboid Intercostal Block vs Serratus Posterior Superior Intercostal Plane Block for VATS Pain
This study tests two regional anesthesia techniques to see which better reduces postoperative pain after video-assisted thoracic surgery in adults undergoing thoracic procedures.
-
Erector Spinae Block vs Paravertebral Block for Chronic Pain After Mastectomy
This trial tests whether an erector spinae block can better prevent chronic pain after mastectomy than a paravertebral block in adults 18–80.
-
Ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block for shoulder arthroscopy pain
This will test whether an ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block reduces pain after arthroscopic shoulder surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.