Comparing two pain management techniques after knee surgery

Comparative Study Between Ultrasound-Guided IPACK Block (Interspace Between the Popliteal Artery and the Posterior Capsule of the Knee) with Adductor Canal Block Versus Adductor Canal Block Alone for Postoperative Pain Management in Total Knee Arthroplasty

Phase 1 Interventional Ain Shams University · NCT06783712

This study is testing whether using a combination of two pain management techniques after knee surgery can help patients feel less pain and wait longer before needing extra pain relief compared to using just one technique.

Quick facts

PhasePhase 1
Study typeInterventional
Enrollment60 (estimated)
Ages20 Years to 60 Years
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06783712 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of combining an ultrasound-guided IPACK block with an adductor canal block versus using the adductor canal block alone for managing postoperative pain in patients undergoing total knee arthroplasty. Patients will be assessed preoperatively and monitored during surgery to ensure proper anesthesia and pain management. The primary outcome will be the time until the first dose of rescue analgesia is needed, along with pain assessment using a numerical rating scale (NRS).

Who should consider this trial

Good fit: Ideal candidates are patients scheduled for total knee arthroplasty who meet the inclusion criteria.

Not a fit: Patients with a history of coagulopathy, neuromuscular disorders, or those who refuse consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and faster recovery for patients after knee surgery.

How similar studies have performed: Previous studies have shown promising results with similar pain management techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

-

Exclusion Criteria:

* The patient refusal to give written consent.
* Previously known allergy to one of the drugs being used in the study.
* Physical status: ASA grades more than III
* History or evidence of coagulopathy, use of anti-coagulant or anti-platelet therapy.
* Patients with neuromuscular disorders
* Injection site infection.

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions The Time Interval Between Injection of the Block and the First Rescue Analgesia Dose Given. Postoperative Pain Assessment Using NRS Score for Pain
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.