Comparing two oral medications for treating a skin fungal infection
Comparison of Efficacy of Oral Fluconazole Versus Oral Itraconazole in the Treatment of Pityriasis Versicolor
PHASE4 · Khyber Teaching Hospital · NCT06922344
This study is testing which of two oral antifungal medications, fluconazole or itraconazole, works better for treating pityriasis versicolor, a common skin fungal infection.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 106 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Khyber Teaching Hospital (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Peshawar, KPK) |
| Trial ID | NCT06922344 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two oral antifungal medications, fluconazole and itraconazole, in treating pityriasis versicolor, a common fungal skin infection. It aims to determine which of the two systemic treatments is more effective for patients suffering from this condition. The study will involve patients diagnosed with pityriasis versicolor and will exclude those with certain health conditions or recent antifungal treatments. The results could provide valuable insights into optimal treatment options for this skin condition.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with pityriasis versicolor who do not have any exclusionary health conditions.
Not a fit: Patients with chronic renal or liver disease, malignancy, or those undergoing chemotherapy or radiotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the more effective treatment for pityriasis versicolor, improving patient outcomes.
How similar studies have performed: Other studies have explored the efficacy of antifungal treatments, but this specific comparison of fluconazole and itraconazole is less common, making it a valuable investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All cases of Pityriasis versicolor Exclusion Criteria: * Patients with history of chronic renal or liver disease, malignancy , or undergoing any kind of chemotherapy or radiotherapy or having cardiac conduction abnormalities. * Patients who received any anti-fungal therapy in the last one month. * Pregnant or lactating women.
Where this trial is running
Peshawar, KPK
- Khyber Teaching Hospital — Peshawar, KPK, Pakistan (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pityriasis Versicolor, Fluconazole, Itraconazole