Comparing two neuromuscular monitoring devices during surgery
Official title: Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor：a Pilot Study
Run by Huazhong University of Science and Technology · NCT05632107 · Data updated 2026-11-12
This study is testing a new device that combines two methods for checking muscle function during surgery to see if it works better than a common monitor used today.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Huazhong University of Science and Technology Academic / other |
| Locations | 2 sites (Wuhan, Hubei and 1 other locations) |
| Status | Recruiting |
| Started | March 1, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2027 |
| Registry record updated | April 3, 2026 |
| Trial ID | NCT05632107 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients under 18 years old, classified as ASA Physical Status I to III, and scheduled for elective surgery that requires muscle relaxation.
✕Probably not a fit
Patients with known neuromuscular disorders, a history of allergic reactions to neuromuscular blocking agents, or those on medications affecting neuromuscular transmission may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates a new device that combines acceleromyography (AMG) and electromyography (EMG) for monitoring neuromuscular blockade during elective surgeries. The goal is to determine the validity of this device in accurately assessing neuromuscular function and preventing residual effects after surgery. By comparing it to the widely used TOF-Watch® monitor, the study aims to improve the reliability and ease of neuromuscular monitoring in clinical practice. Participants will include patients undergoing elective surgery requiring muscle relaxation.
Why it matters
Potential benefit: If successful, this study could enhance the safety and effectiveness of neuromuscular monitoring, reducing the risk of complications from residual neuromuscular blockade.
How similar studies have gone: While the use of EMG in neuromuscular monitoring is gaining attention, this specific combination of AMG and EMG has not been previously reported, making this approach novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age less than 18 yr * American Society of Anesthesiologists Physical Status I to III * Elective surgery requiring muscle relaxation * Patients participated voluntarily and signed informed consent Exclusion Criteria: * Patients with known neuromuscular disorder * Stroke * Patients with a history of allergic reaction toneuromuscular blocking agents * Use of medications that might interfere with neuromuscular transmission * Any previous injury to the examined arm that might influence nerve conduction parameters * Pacemaker
Where it's running
-
Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China Recruiting -
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China Recruiting
Study contacts
- Study coordinator: Hua Zheng, Dr.
- Email: hzheng@hust.edu.cn
- Phone: 0086-27-83663173
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
NMTCuff vs standard TOF monitoring during gynecologic oncology surgery
This study tests whether NMTCuff monitoring can better detect neuromuscular recovery than standard TOF monitoring in women undergoing laparoscopic gynecologic cancer surgery.
-
HRS-9190 vs Rocuronium for Muscle Relaxation During Anesthesia
This Phase 3 trial tests whether HRS-9190 can provide effective muscle relaxation for intubation and surgery as compared with rocuronium in adults undergoing elective general anesthesia.
-
Two EMG Monitors for Deep NMB During Robotic/Thoracic Surgery
This study tests whether two quantitative EMG monitors (TetraGraph and TwitchView) can better maintain deep neuromuscular blockade during abdominal and thoracic surgery by comparing diaphragmatic movements and breath-initiation events in the same patient.
-
Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Monitoring
This study tests whether keeping a low, controlled amount of rocuronium during spine surgery helps nerve monitoring while improving the surgical field compared to stopping rocuronium after induction.
-
Safer muscle relaxant and reversal choice during anesthesia for people with chronic kidney disease
This trial will try to see if using cisatracurium with neostigmine leads to fewer breathing problems after surgery than using rocuronium with sugammadex in adults who have chronic kidney disease.
-
Comparing muscle responses for monitoring neuromuscular function after surgery
This study is testing a device to see if it can better monitor muscle function after surgery for patients who have received a specific muscle relaxant.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.