Comparing two neuromuscular monitoring devices during surgery
Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor：a Pilot Study
This study is testing a new device that combines two methods for checking muscle function during surgery to see if it works better than a common monitor used today.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Huazhong University of Science and Technology Academic / other |
| Locations | 2 sites (Wuhan, Hubei and 1 other locations) |
| Trial ID | NCT05632107 on ClinicalTrials.gov |
What this trial studies
This study evaluates a new device that combines acceleromyography (AMG) and electromyography (EMG) for monitoring neuromuscular blockade during elective surgeries. The goal is to determine the validity of this device in accurately assessing neuromuscular function and preventing residual effects after surgery. By comparing it to the widely used TOF-Watch® monitor, the study aims to improve the reliability and ease of neuromuscular monitoring in clinical practice. Participants will include patients undergoing elective surgery requiring muscle relaxation.
Who should consider this trial
Good fit: Ideal candidates are patients under 18 years old, classified as ASA Physical Status I to III, and scheduled for elective surgery that requires muscle relaxation.
Not a fit: Patients with known neuromuscular disorders, a history of allergic reactions to neuromuscular blocking agents, or those on medications affecting neuromuscular transmission may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the safety and effectiveness of neuromuscular monitoring, reducing the risk of complications from residual neuromuscular blockade.
How similar studies have performed: While the use of EMG in neuromuscular monitoring is gaining attention, this specific combination of AMG and EMG has not been previously reported, making this approach novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age less than 18 yr * American Society of Anesthesiologists Physical Status I to III * Elective surgery requiring muscle relaxation * Patients participated voluntarily and signed informed consent Exclusion Criteria: * Patients with known neuromuscular disorder * Stroke * Patients with a history of allergic reaction toneuromuscular blocking agents * Use of medications that might interfere with neuromuscular transmission * Any previous injury to the examined arm that might influence nerve conduction parameters * Pacemaker
Where this trial is running
Wuhan, Hubei and 1 other locations
- Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China (Recruiting)
- Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China (Recruiting)
Study contacts
- Study coordinator: Hua Zheng, Dr.
- Email: hzheng@hust.edu.cn
- Phone: 0086-27-83663173
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.