Comparing two nerve blocks for pain control after knee replacement
Investigation of the Effectiveness of Adductor Canal Block and Suprainguinal Fascia Iliaca Block in Patients Planned for Total Knee Arthroplasty
This study will see if a suprainguinal fascia iliaca plane block or an adductor canal block gives better pain relief after total knee replacement for adults having spinal anesthesia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 86 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Tokat Gaziosmanpasa University Academic / other |
| Locations | 1 site (Tokat Province, ABD Veya Kanada'daysanız Lütfen Seçin...) |
| Trial ID | NCT07040709 on ClinicalTrials.gov |
What this trial studies
Adults aged 18–75 scheduled for total knee arthroplasty under spinal anesthesia are randomized to receive either an ultrasound-guided suprainguinal fascia iliaca plane block or an adductor canal block performed by a single investigator. Postoperative pain scores, opioid consumption via patient-controlled analgesia (PCA), and recovery metrics are recorded by a blinded assessor. Standard perioperative monitoring and multimodal analgesia (intravenous paracetamol, tramadol PCA, and diclofenac as rescue) are used. Patients with chronic pain, allergies to local anesthetics or opioids, bleeding disorders, or psychiatric conditions that impair cooperation are excluded.
Who should consider this trial
Good fit: Adults 18–75 years old with ASA physical status I–III scheduled for total knee arthroplasty under spinal anesthesia are the intended participants.
Not a fit: Patients with chronic pain conditions, allergies to local anesthetics or opioids, bleeding disorders or anticoagulant use, psychiatric conditions that impair cooperation, or those unwilling to participate are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If one block proves better, patients could have improved postoperative pain control with lower opioid use and faster recovery after knee replacement.
How similar studies have performed: Previous studies of peripheral nerve blocks for knee arthroplasty have reported mixed results, so direct comparisons between these specific blocks remain unresolved.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 75 years * Patients classified as ASA I, II, or III based on physical status * Patients scheduled for total knee arthroplasty under spinal anesthesia Exclusion Criteria: * Patients with chronic pain conditions. * Patients with a history of allergy to opioids or local anesthetics. * Patients with psychiatric disorders that may impair cooperation. * Patients with bleeding disorders or those using anticoagulant therapy. * Patients unwilling to participate voluntarily in the study.
Where this trial is running
Tokat Province, ABD Veya Kanada'daysanız Lütfen Seçin...
- Tokat Gaziosmanpasa University — Tokat Province, ABD Veya Kanada'daysanız Lütfen Seçin..., Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Ali Genç, Assistant professor
- Email: aligenc0860@outlook.com
- Phone: +90-3562129500
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.