Comparing two nerve-block approaches for pain after anterior-approach hip replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial enrolls adults undergoing elective anterior-approach total hip arthroplasty and randomizes them to receive either a PENG block plus a lateral femoral cutaneous nerve (LFCN) block or a PENG block plus wound infiltration. All patients receive spinal anesthesia and the regional techniques are performed as part of routine perioperative care. The primary outcome is pain at rest on a numerical rating scale six hours after surgery, and secondary outcomes include dynamic pain at multiple time points, total opioid consumption, time to first rescue analgesia, quadriceps strength, hip flexion angle, length of stay, and adverse events. Safety will be continuously monitored by the principal investigator and study team according to an internal safety plan.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years
* Elective total hip arthroplasty
* Spinal (subarachnoid) anesthesia
* Written informed consent provided by the patient or by the legal guardian, if appointed

Exclusion Criteria:

* INR \> 1.5
* aPTT \> 1.5
* Platelet count \< 75,000/mm³
* Signs suggestive of infection at the puncture site
* Absence of informed consent to the procedure
* Documented or suspected allergy to local anesthetics

Where it's running

• Ospedale Edoardo Bassini
  Cinisello Balsamo, Milano, Italy Recruiting

Study contacts

• Study coordinator: Matteo Coccolo, MD
• Email: matteo.coccolo@asst-nordmilano.it
• Phone: 0039025799

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.