Comparing two minimally invasive surgical techniques for esophageal cancer
A Comparison of Short-term and Long- Term Outcomes Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy
This study is testing which of two minimally invasive surgical techniques works better for people with lower esophageal cancer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 30 Years to 80 Years |
| Sex | All |
| Sponsor | The Second Hospital of Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT04217239 on ClinicalTrials.gov |
What this trial studies
This clinical trial compares the safety and effectiveness of two minimally invasive esophagectomy techniques, the Ivor-Lewis and McKeown approaches, for treating lower thoracic esophageal cancer and esophageal-gastric junction tumors. The study aims to evaluate short-term and long-term outcomes, including complication rates and overall feasibility of each surgical method. By focusing on patients with clinically staged T1-3N0-2M0 tumors, the trial seeks to provide insights into which approach may offer better results for patients undergoing surgery for esophageal cancer.
Who should consider this trial
Good fit: Ideal candidates are patients with lower thoracic esophageal tumors and good cardiopulmonary function, without a history of previous cancer or neck/chest surgery.
Not a fit: Patients with poor cardiopulmonary function or those who have undergone hybrid minimally invasive esophagectomy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients with esophageal cancer.
How similar studies have performed: Previous studies have shown promising results with minimally invasive approaches for esophageal cancer, suggesting potential for success in this comparative analysis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: (I) Patients with clinically staged T1-3N0-2M0 tumors; good cardiopulmonary function; (II) Patients with lower thoracic esophageal tumors and esophageal- gastric junction tumor; (III) Patients without a previous history of cancer; (IV) Patients without a previous history of neck or chest surgery; Exclusion Criteria: (I) cardiopulmonary function not good enough for surgery; (II) Patients with hybrid MIE
Where this trial is running
Jinan, Shandong
- Yunpeng Zhao — Jinan, Shandong, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.