Comparing two methods of pain relief after knee surgery
Continuous Distal Adductor Canal Block With Periarticular Local Anesthetic Infiltration Versus Continuous Distal Adductor Canal Block Alone for Analgesia After Total Knee Arthroplasty
This study is testing if adding a local anesthetic injection to a nerve block can help people feel less pain after knee surgery compared to just using the nerve block alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | Yonsei University Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT05427019 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of continuous distal adductor canal block combined with periarticular local anesthetic infiltration versus the distal adductor canal block alone for managing postoperative pain in patients undergoing total knee arthroplasty. Sixty-six patients will be randomly assigned to receive either the combined treatment or the single treatment. The aim is to determine if the addition of periarticular infiltration enhances pain relief compared to the adductor canal block alone. The study focuses on the analgesic effects on posterior knee pain, which is a common issue after knee surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 19 and older scheduled for elective unilateral total knee arthroplasty with an ASA physical status of 1-3.
Not a fit: Patients with allergies to study drugs, hepatic or renal insufficiency, opioid dependency, coagulopathy, pre-existing neurologic deficits, or severe psychiatric illness may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management for patients recovering from total knee arthroplasty.
How similar studies have performed: Previous studies have shown promising results with similar analgesic techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients aged 19 years old or older, with American Society of Anesthesiologists Physical Status 1-3, and scheduled for elective unilateral total knee arthroplasty Exclusion Criteria: 1. Allergy or intolerance to any of the drugs used in the study 2. Hepatic or renal insufficiency 3. Opioid dependency 4. Coagulopathy 5. Pre-existing neurologic or anatomic deficits in the lower extremities 6. Severe psychiatric illness
Where this trial is running
Seoul
- Yonsei University Health System, Severance Hospital — Seoul, Korea, Republic of (Recruiting)
Study contacts
- Principal investigator: Yong Seon Choi — Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine
- Study coordinator: Yong Seon Choi
- Email: yschoi@yuhs.ac
- Phone: 82-2-2224-3919
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.