Comparing two methods of pain relief after hip surgery

A Comparative Study Between the Postoperative Analgesic Effect of Pericapsular Nerve Group Block (PENG) and Fascia Iliaca Compartment Block (FICB) in Total Hip Arthroplasty: a Prospective Randomized Clinical Trial

This study tests which of two pain relief methods works better for people having hip surgery to help them feel less pain and use fewer narcotics after their operation.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 68 (estimated)
• Ages: 18 Years to 80 Years
• Sex: All
• Sponsor: Ain Shams University (other)
• Locations: 1 site (Cairo)
• Trial ID: NCT06003738 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of two regional anesthesia techniques, the pericapsular nerve block and the fascia iliaca compartment block, in managing postoperative pain for patients undergoing total hip arthroplasty. The aim is to reduce narcotic consumption and pain intensity during the first 24 hours post-surgery, using the Visual Analogue Scale for assessment. Both techniques are designed to provide effective analgesia while minimizing complications and preserving motor function. The study will include patients aged 18-80 scheduled for total hip arthroplasty under spinal anesthesia.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-80 who are scheduled for total hip arthroplasty and meet the ASA Physical Status Class I, II, or III criteria.

Not a fit: Patients with significant cognitive dysfunction, psychiatric disorders, or contraindications to regional anesthesia will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing hip surgery, reducing reliance on narcotics.

How similar studies have performed: Previous studies have shown promising results with both pericapsular nerve blocks and fascia iliaca compartment blocks in similar surgical contexts.

Eligibility criteria

Inclusion Criteria:

1. Age 18-80 years.
2. Sex: Both sexes.
3. American Society of Anaesthesiologists (ASA) Physical Status Class I, II, and III.
4. Scheduled for Total hip arthroplasty (THA) under spinal anesthesia.

Exclusion Criteria:

1. Declining to give a written informed consent.
2. History of allergy to the medications used in the study.
3. Contraindications to regional anesthesia (including patient refusal, coagulopathy, and local infection).
4. Psychiatric disorders.
5. Significant cognitive dysfunction.
6. American Society of Anesthesiologists (ASA) Physical Status Class IV.
7. Liver failure, renal insufficiency (estimated glomerular filtration rate \< 15 mL/min/1.73 m2).
8. Patients who had failed spinal anaesthesia were excluded from the study.
9. Pregnancy.

Where this trial is running

Cairo

• Ain shams university hospitals — Cairo, Egypt (RECRUITING)

Study contacts

• Principal investigator: Diaaeldin DA Aboelnile, MD, Lecturer — Faculty of Medicine, Ain Shams University
• Study coordinator: Diaaeldin DA Aboelnile, MD, Lecturer

Conditions: Anesthesia