Comparing two methods of pain relief after bladder surgery
Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy: Prospective-randomized Clinical Trial
This study is testing two different ways to give pain relief after bladder surgery to see which one works better for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 40 Years to 70 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Trial ID | NCT05089994 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of two ultrasound-guided approaches for administering a quadratus lumborum block (QLB) to manage postoperative pain in patients undergoing radical cystectomy. The two techniques being compared are the anterior approach and the intramuscular approach, which involves injecting local anesthetics directly into the quadratus lumborum muscle. The study will assess the analgesic outcomes of these methods to determine which provides better pain relief after surgery. The research is particularly relevant given the higher incidence of bladder cancer in certain regions, emphasizing the need for effective pain management strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 40-70 years with a BMI between 20-30 who are scheduled for radical cystectomy.
Not a fit: Patients with a BMI over 30, chronic pain syndromes, or those on prolonged opioid medication may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative pain management for patients undergoing radical cystectomy.
How similar studies have performed: Previous studies have shown effective postoperative analgesia with various approaches to quadratus lumborum block, indicating that this method has potential based on existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: 40-70years. * BMI: 20-30 kg.m2 * Sex: both males and females. * American Society of Anesthesiologists (ASA )physical status: I-III. * Operation: radical cystectomy Exclusion Criteria: * • Patient's refusal to participate in the study. * known allergy to local anesthesia (LA), * coagulopathy or thrombocytopenia, * body mass index (BMI) above 30 kg .m 2, and infection at site of injection. * Chronic pain syndromes, * Prolonged opioid medication, * Patients on regular use of analgesic or who received analgesic 24 h before surgery
Where this trial is running
Asyut
- Assuit university urology hospital — Asyut, Egypt (Recruiting)
Study contacts
- Study coordinator: Hassan Mostafa abdelbaky ahmed, Master
- Email: hassan.mostafa9444@gmail.com
- Phone: 01060264751
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.