Comparing two methods of injecting triamcinolone to treat subglottic stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is a multicenter, randomized controlled trial that aims to compare the effectiveness and safety of two different injection techniques for treating subglottic stenosis: translaryngeal endoscopic mucosal injection and ultrasound-guided injection of triamcinolone. Patients diagnosed with subglottic stenosis will be randomly assigned to one of the two treatment groups. The study will evaluate various outcomes, including therapeutic effects, adverse reactions, treatment costs, and hospital resource utilization, to determine which method is superior. The goal is to provide evidence-based recommendations for the best treatment approach for this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1: "Diagnosed with subglottic stenosis through laryngoscopic examination or imaging studies such as CT."
* 2: "Experiencing symptoms related to subglottic stenosis, such as breathing difficulties, hoarseness, etc."

Exclusion Criteria:

* 1: "Severe cardiopulmonary dysfunction, patients extremely debilitated and unable to tolerate the procedure."
* 2: "Patients allergic to lidocaine, midazolam, triamcinolone, or any of their components."
* 3: "Pregnant or lactating women."
* 4: "Unstable angina, congestive heart failure, severe bronchial asthma."
* 5: "Severe hypertension and arrhythmias, hemodynamically unstable, and severe respiratory failure (PaO2 \<60mmHg after oxygen therapy or mechanical ventilation)."
* 6: "Known coagulation dysfunction, inability to stop anticoagulants, antiplatelet agents, aspirin, or nonsteroidal anti-inflammatory drugs before treatment."
* 7: "Patients do not agree to participate in this study."
* 8: "Participation in other studies within the last three months and not withdrawn or concluded, or having received triamcinolone treatment less than 1 month ago."
* 9: "Researchers believe there are any circumstances making the patient unsuitable for inclusion."

Where it's running

• China-Japan Friendship Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Gang Hou, PI
• Email: hougangcmu@163.com
• Phone: 01084206250

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.