Comparing two methods for treating soft tissue issues around dental implants
Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial
PHASE2 · Tanta University · NCT06588998
This study is testing whether a new type of membrane or a tissue graft works better for treating soft tissue problems around dental implants in adults aged 20 to 50.
Quick facts
| Phase | PHASE2 |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 20 Years to 50 Years |
| Sex | All |
| Sponsor | Tanta University (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Tanta, Gharbia Governorate) |
| Trial ID | NCT06588998 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of Xengenic cortical membranes and connective tissue grafts with coronally advanced flaps in treating peri-implant soft tissue dehiscences, a common complication in implant dentistry. The study will involve adults aged 20-50 with specific inclusion criteria, focusing on their compliance and gingival phenotype. By assessing patient outcomes, the trial seeks to identify the optimal treatment modality for improving soft tissue regeneration and clinical results.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 20-50 with peri-implant soft tissue dehiscences and a thin gingival phenotype.
Not a fit: Patients who are medically compromised, smokers, diabetics, pregnant or lactating women, or those with a history of chemotherapy or bisphosphonate therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients experiencing soft tissue complications around dental implants.
How similar studies have performed: While there is a need for comparative studies in this area, the specific approaches being tested in this trial have not been widely studied together, making this a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (20-50) years old. •peri-implant soft tissue dehiscence . •Thin gingival phenotype. •Optimal compliance as evidenced by no missing treatment appointments and positive attitude towards oral hygiene. Exclusion Criteria: * •Medically compromised patients and systemic conditions precluding implant and periodontal surgery. •Smokers, diabetics, pregnant or lactating women. •History of chemotherapy, radiotherapy in head and/or neck region. •Bisphosphonate therapy.
Where this trial is running
Tanta, Gharbia Governorate
- TantaU — Tanta, Gharbia Governorate, Egypt (RECRUITING)
Study contacts
- Study coordinator: amr anwar ellithy, MSC
- Email: amr.yousef@dent.tanta.edu.eg
- Phone: 00201066767062
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Immediate Implant, Connective Tissue Graft