Comparing two methods for treating knee osteoarthritis pain
Comparison of the Effectiveness of Conventional and Cooled Radiofrequency Ablation in Advanced Knee Osteoarthritis
This study is testing whether a new cooling method for treating knee pain works better than the standard method for people aged 50 to 80 with long-lasting knee osteoarthritis pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 26 (estimated) |
| Ages | 50 Years to 80 Years |
| Sex | All |
| Sponsor | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital Academic / other |
| Locations | 1 site (Ankara, Çankaya) |
| Trial ID | NCT06863181 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness of conventional and cooled radiofrequency ablation in alleviating pain and disability in patients suffering from knee osteoarthritis. Participants will be individuals aged 50 to 80 with knee pain lasting over six months that has not responded to other treatments. The study will assess the outcomes of both treatment methods to determine which is more effective for managing pain in this patient population.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50 to 80 with chronic knee pain due to grade III or IV osteoarthritis that has not responded to conservative treatments.
Not a fit: Patients with a history of knee surgery, trauma, or systemic inflammatory diseases affecting the knee may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients with knee osteoarthritis who have not found relief from conventional therapies.
How similar studies have performed: Other studies have shown promising results with radiofrequency ablation for pain management, suggesting that this approach may be effective, though the comparison of conventional versus cooled methods is less commonly explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Knee pain lasting more than 6 months * Age between 50 and 80 * Diagnosis of radiographically proven grade III or IV knee osteoarthritis according to the Kellgren-Lawrence Grading Scale, marked narrowing of the medial compartment of the tibiofemoral joint space * Presence of pain resistant to conservative treatment * Exercise * Physical therapy agents * Use of oral anti-inflammatory agents Exclusion Criteria: * History of trauma to the knee area * History of knee surgery * Presence of systemic inflammatory disease affecting the knee joint * Presence of peripheral neuropathy or radiculopathy * Pregnancy * Hemodynamic instability * Presence of skin or soft tissue infection at the injection site * Refusal to participate in the study * Presence of acute knee pain with accompanying inflammatory findings * Presence of a serious psychiatric disorder or neurological disease Having received an intra-articular injection within the last 3 months
Where this trial is running
Ankara, Çankaya
- Gaziler Physical Medicine and Rehabilitation Training and Research Hospital — Ankara, Çankaya, Turkey (Recruiting)
Study contacts
- Study coordinator: Ayşe Naz Kalem Özgen, Specialist
- Email: kalemnaz@gmail.com
- Phone: 03122911000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.