Comparing two methods for treating gum recession on lower front teeth
Comparison of Surgical Techniques to Treat Isolated Gingival Recession in Mandibular Incisors: A Randomized Clinical Trial
NA · Case Western Reserve University · NCT06037161
This study is testing two different surgical methods for treating gum recession on the lower front teeth to see which one works better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 36 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Case Western Reserve University (other) |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT06037161 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of two surgical techniques for treating isolated gingival recession in mandibular incisors: the Coronally Advanced Flap (CAF) combined with a Connective Tissue Graft (CTG) and the Gingival Pedicle Split Thickness flap (GPST) with CTG. The study will measure the mean root coverage achieved by both methods, as well as the percentage of complete root coverage and keratinized tissue gain after six months. Participants will undergo clinical assessments at baseline and follow-up to evaluate the outcomes of each technique.
Who should consider this trial
Good fit: Ideal candidates are healthy adults over 18 with specific types of gum recession in their lower front teeth.
Not a fit: Patients with uncontrolled diabetes, active smoking habits, or other contraindications to periodontal surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective surgical option for patients suffering from gum recession, leading to improved oral health and aesthetics.
How similar studies have performed: Preliminary data from similar techniques suggest promising outcomes, indicating that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males and females of \> 18 years of age * Single Cairo's RT1 (Recession Type 1) and RT2 ( Recession Type 2) recession defects (≥3 mm in depth) in mandibular anterior teeth (Incisors). * Presence of identifiable cemento-enamel junction (CEJ) * Presence of a step ≤1 mm at the CEJ level and/or the presence of a root abrasion, but with an identifiable CEJ, will be accepted * Periodontally and systemically healthy patients * No contraindications for periodontal surgery and not taking medications known to interfere with periodontal tissue health or healing; and no prior periodontal surgery on the involved sites Exclusion Criteria: * Vaping, chewing tobacco or smoking \> 10 cigarettes per day * Uncontrolled Diabetes Mellitus (HbA1c \> 7) * Pregnancy and Lactation * Diseases affecting connective tissue metabolism * Long-term steroid use * Recession defects associated with caries * Teeth associated with pulpal pathology
Where this trial is running
Cleveland, Ohio
- Case Western Reserve University School of Dental Medicine — Cleveland, Ohio, United States (RECRUITING)
Study contacts
- Principal investigator: Gian Pietro Schincaglia, DDS, PhD — Case Western Reserve University
- Study coordinator: Gian Pietro Schincaglia, DDS,PhD
- Email: gxs486@case.edu
- Phone: 2163684412
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Recession, Gingival, Connective tissue graft, cosmetic periodontal plastic surgery, gingival recession, mucogingival surgery, treatment planning