Comparing two methods for reducing discomfort during intubation in anesthesia
Discomfort in Upper Airways Due to intubation-a Randomized Controlled Trial in a Norwegian Hospital
This study is testing whether using a muscle relaxant or a local anesthetic spray before intubation can help reduce discomfort and hoarseness in patients undergoing anesthesia for certain procedures.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Ostfold University College Academic / other |
| Locations | 1 site (Kråkerøy, Østfold) |
| Trial ID | NCT05614609 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of two different methods for intubation during general anesthesia in gastro- or gynecological procedures. Participants will be randomly assigned to receive either a muscle relaxant (rocuronium) or a local anesthetic spray (lidocaine) on the glottis before intubation. The primary focus is to assess postoperative hoarseness and discomfort in the upper airways one hour after intubation. The study addresses a gap in current research regarding optimal intubation techniques and aims to provide clearer guidelines for anesthetic practices.
Who should consider this trial
Good fit: Ideal candidates are patients classified as ASA I-III who are undergoing gastro- or gynecological procedures under general anesthesia.
Not a fit: Patients with a BMI above 40, anticipated difficult intubation, or those with known allergies to lidocaine or muscle relaxants may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved intubation techniques that minimize discomfort for patients undergoing surgery.
How similar studies have performed: While there is limited research on this specific comparison, previous studies have indicated a need for further investigation into optimal intubation methods, suggesting this approach is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA (American Association of Anesthesiologists Classification system for physical status) I-III * Understand and can express themselves in Norwegian * Able to give informed consent to participate Exclusion Criteria: * Cave lidocain and/or muscle relaxing medication * BMI above 40 * Anticipated difficult intubation * Need for ventricular tube * Pathology or malformations in upper airways
Where this trial is running
Kråkerøy, Østfold
- Ann-Chatrin Linqvist Leonardsen — Kråkerøy, Østfold, Norway (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.