Comparing two methods for preserving jawbone after tooth extraction
Evaluation of Post Extraction Hard Tissue Alteration Following Ridge Preservation Using Partially Demineralized Dentin Block Versus Xenograft in the Esthetic Zone: A Randomized Controlled Clinical Trial
NA · Cairo University · NCT06429540
This study is testing whether using a special type of block or a different material after tooth extraction can better preserve the jawbone for patients with teeth that can't be saved.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 22 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo, Elmanil) |
| Trial ID | NCT06429540 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the changes in hard tissue dimensions following tooth extraction when using either a Partially Demineralized Dentin Block or a Xenograft for ridge preservation in the esthetic zone. Patients with non-restorable teeth will undergo a thorough preoperative assessment, including clinical and radiographic examinations, before being randomly assigned to one of the two treatment groups. Both groups will experience atraumatic tooth extraction, and the effectiveness of each method will be assessed through clinical and radiographic evaluations at multiple time points. The study is conducted at the Faculty of Dentistry, Cairo University.
Who should consider this trial
Good fit: Ideal candidates are healthy patients with non-restorable teeth in the esthetic zone and good oral hygiene.
Not a fit: Patients with systemic conditions affecting healing, poor oral hygiene, or heavy smokers may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective method for preserving jawbone structure after tooth extraction, improving outcomes for patients requiring dental implants.
How similar studies have performed: Other studies have shown promising results with similar ridge preservation techniques, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with non-restorable teeth and Type II extraction socket in the esthetic zone * Healthy patients with adequate oral hygiene (bleeding on probing ≤20%; Plaque index ≤20%). * Systemically healthy. Exclusion Criteria: * Heavy smokers (more than 10 cigarettes per day or an electronic cigarette dose of \>6 mg/ml of nicotine). * Patients reporting systemic conditions that may compromise healing or bone metabolism (eg: diabetes). * Patients with poor oral hygiene (bleeding on probing \>20%; Plaque index \>20%) * The presence of acute periapical infection. * The presence of severe periodontal destruction.
Where this trial is running
Cairo, Elmanil
- Faculty of dentistry Cairo University — Cairo, Elmanil, Egypt (RECRUITING)
Study contacts
- Study coordinator: Danah Al Ghothani, Bachelor
- Email: danah.tayseer@dentistry.cu.edu.eg
- Phone: 1026826826
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Socket Preservation, L-PRF, Xenograft, Collagen membrane, Dentin block, Partially demineralized dentin block, Socket preservation, Liquid fibrinogen