Comparing two methods for preserving bone after tooth extraction
Evaluation of Post Extraction Hard Tissue Alteration Following Ridge Preservation in the Esthetic Zone Using Allogeneic Dentin Matrix Versus Demineralized Freeze-Dried Bone Allograft: A Randomized Controlled Clinical Trial
NA · Cairo University · NCT06318650
This study is testing whether using two different types of bone grafts after tooth extraction helps preserve the jawbone better in patients needing dental work in the front of their mouth.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 22 (estimated) |
| Ages | 20 Years to 55 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06318650 on ClinicalTrials.gov |
What this trial studies
This study evaluates the differences in clinical, radiographic, and histomorphometrical outcomes between using Allogenic Demineralized Dentin Matrix and Demineralized Freeze-Dried Bone Allograft (DFDBA) for alveolar ridge preservation following tooth extraction in the esthetic zone. Patients will undergo initial periodontal treatment before receiving either of the two graft materials during a flapless tooth extraction procedure. The study aims to determine which method is more effective in managing post-extraction hard tissue changes. Participants will be monitored for six months to assess the outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20-55 with a single rooted, non-restorable tooth requiring extraction and minimal buccal bone loss.
Not a fit: Patients with uncontrolled systemic diseases, severe para-functional habits, or those who smoke may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve bone preservation techniques, leading to better outcomes for dental implants.
How similar studies have performed: Previous studies have shown varying success with similar grafting techniques, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients between the age of 20-55. * Single rooted, non-restorable or hopeless tooth with adjacent teeth. * Extraction socket with no more than 50% buccal bone loss * Patients accept 6-months follow-up period (cooperative patients). * Patients provide an informed consent. Exclusion Criteria: * Patients with uncontrolled systemic disease. * Patient with severe para-functional habits. * Patients with poor maintenance of oral hygiene. * Pregnancy. * Smokers. * Patients taking any medications that could compromise healing.
Where this trial is running
Cairo
- Faculty of Dentistry Cairo University — Cairo, Egypt (RECRUITING)
Study contacts
- Principal investigator: Fatima M. Saleem Bin Nuhaid, Bachelor — Cairo University
- Study coordinator: Fatima M. Saleem Bin Nuhaid, Bachelor
- Email: fatima.mubarak@dentistry.cu.edu.eg
- Phone: +201017873596
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Socket Preservation, Socket preservation, Ridge preservation, Allogeneic dentin matrix, Demineralized freeze dried bone allograft, DFDBA