Comparing two methods for preserving bone after tooth extraction

Evaluation of Socket Seal Using Flowable Composite Above Xenograft Compared to Dense Polytetrafluoroethylene (d-PTFE) Membrane in Ridge Preservation Procedures: a Randomized Controlled Clinical Trial

Not applicable Interventional Cairo University · NCT06315413

This study is testing whether using a special resin or a different type of membrane after tooth extraction helps patients keep their bone better and feel more satisfied with the results.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages20 Years to 70 Years
SexAll
SponsorCairo University Academic / other
Drugs / interventionsradiation
Locations1 site (Cairo, Cairo Governorate)
Trial IDNCT06315413 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of using flowable resin composite versus dense polytetrafluoroethylene (d-PTFE) membranes for socket sealing in patients undergoing tooth extraction. Participants will have their extraction sites filled with xenograft particles, and the study will assess changes in soft and hard tissue, procedural time, postoperative pain, patient satisfaction, and cost-effectiveness. The goal is to determine which method provides better outcomes for socket preservation and simplifies the procedure.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20 to 70 with a single non-adjacent hopeless maxillary tooth in the esthetic zone indicated for extraction and who maintain good oral hygiene.

Not a fit: Patients with systemic diseases affecting bone metabolism, untreated periodontal diseases, or those with para-functional habits like bruxism may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved techniques for preserving bone after tooth extraction, enhancing implant placement success.

How similar studies have performed: Previous studies have explored socket preservation techniques, but this specific comparison of flowable composite resin and d-PTFE membranes is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients having single non-adjacent hopeless maxillary tooth in the esthetic zone that are indicated for extraction.
* Patients with healthy systemic condition.
* Patients aged from 20 to 70 years old.
* Good oral hygiene.
* Accepts 4 months follow-up period (cooperative patients).

Exclusion Criteria:

* Systemic diseases or medications that might affect bone metabolism, increase surgical risk or complicate post-operative healing.
* Previous bone augmentation to implant site.
* Untreated periodontal diseases.
* Para-functional habits such as bruxism and clenching.
* History of radiation therapy to the head and neck.
* Heavy smokers (≥ 10 cigarettes per day).
* Pregnant or lactating females.
* Alcoholism or drug abuse.
* Psychiatric problems.

Where this trial is running

Cairo, Cairo Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alveolar Bone Loss
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.