Comparing two methods for preserving bone after tooth extraction
Evaluation of Post Extraction Hard Tissue Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block in the Esthetic Zone: A Randomized Controlled Pilot Trial
This study is testing two different ways to keep the bone strong after a tooth is taken out to see which method works better for patients with a tooth that can't be saved.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo, Elmanil) |
| Trial ID | NCT06275490 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two different techniques for ridge preservation following tooth extraction in the esthetic zone: partially demineralized dentin block and L-PRF block. Patients with a single non-restorable tooth will undergo a thorough periodontal and radiographic examination before extraction. The study will measure post-extraction hard tissue changes using various dental imaging techniques and clinical assessments. The goal is to determine which method better maintains bone structure after tooth removal.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 18 and older with a single non-restorable tooth in the esthetic zone.
Not a fit: Patients with systemic diseases affecting bone metabolism, heavy smokers, or those with infections at the extraction site may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve outcomes for patients needing tooth extractions by enhancing bone preservation, which is crucial for future dental implants.
How similar studies have performed: Previous studies have shown varying success with similar ridge preservation techniques, but this specific comparison is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged ≥18 years. * Healthy individuals with no medical history. * Patients who have a single non-restorable tooth in the esthetic zone. * Post-extraction socket with four bone walls, the buccal plate is partially missing following extraction of the tooth. (Type II Extraction socket). * Patients capable of understanding or signing the informed consent form before surgery and capable of meeting oral cleaning requirements for implant placement. Exclusion Criteria: * Systemic disease that might impair bone metabolism, antiresorptive therapy (as bisphosphonates),pregnancy, psychiatric conditions. * Heavy smokers (\> 10 cigarettes) * The presence of acute or chronic infection at the site of tooth extraction with lack of treatment for periodontal disease, or x-rays showing loss of alveolar bone on the adjacent teeth.
Where this trial is running
Cairo, Elmanil
- Faculty of dentistry Cairo University — Cairo, Elmanil, Egypt (Recruiting)
Study contacts
- Study coordinator: Alaa Ah Al-Hazmi, Bachelor
- Email: alaa.alhazmi@dentistry.cu.edu.eg
- Phone: +201271952129
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.