Comparing two methods for pain relief after hip surgery

Ultrasound-guided Transmuscular Quadratus Lumborum and Modified Erector Spinae Plane Block Versus Periarticular Infiltration for Pain Management After Total Hip Arthroplasty

NA · Huazhong University of Science and Technology · NCT06688136

This study is testing a new way to relieve pain after hip surgery to see if it works better than the usual method for helping patients recover more comfortably.

Quick facts

PhaseNA
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorHuazhong University of Science and Technology (other)
Locations1 site (Wuhan, Hubei)
Trial IDNCT06688136 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effectiveness of a novel transmuscular quadratus lumborum and modified erector spinae plane (QLESP) block against traditional periarticular infiltration (PAI) for postoperative analgesia in patients undergoing total hip arthroplasty (THA). The study will utilize ultrasound guidance to administer the QLESP block, which is designed to provide efficient pain relief with minimal impact on muscle function. By evaluating pain management outcomes and opioid consumption, the trial seeks to identify the optimal approach for enhancing postoperative recovery.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-65 who are undergoing elective primary unilateral total hip arthroplasty.

Not a fit: Patients with known allergies to the study drugs, pre-existing neuropsychiatric disorders, or contraindications to peripheral nerve blocks may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies that reduce opioid use and enhance recovery after hip surgery.

How similar studies have performed: Previous studies have shown promising results with regional anesthesia techniques in postoperative pain management, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 18-65 yrs
2. American Society of Anesthesiologists classification 1-3
3. Body mass index between 20 and 35 (kg/m2)
4. Undergo elective primary unilateral THA via a posterolateral approach
5. Informed consent

Exclusion Criteria:

1. A known allergy to the drugs being used
2. Pre-existing neuropsychiatric disorders or language barrier
3. Analgesics intake, history of substance abuse
4. Contraindications to peripheral nerve block
5. Acute cerebrovascular disease
6. Severe liver failure

Where this trial is running

Wuhan, Hubei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Regional Anaesthesia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.