Comparing two methods for pain relief after hip replacement surgery
The Effect of Unilateral Erector Spinae Plane Block Versus Intrathecal Morphine on Early Mobilization After Total Hip Replacement Under Spinal Anesthesia in Cairo University Hospitals: a Prospective Randomized Clinical Study
This study is testing whether a new pain relief method using a nerve block works better than morphine for helping people manage pain after hip replacement surgery.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06621849 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of a unilateral erector spinae plane block versus intrathecal morphine for managing postoperative pain in patients undergoing hip replacement surgery. A total of 70 adult participants will be randomly assigned to one of two groups, receiving either the erector spinae plane block or morphine as part of their anesthesia regimen. The study aims to assess early mobilization and pain control post-surgery through standardized pain scoring methods. Preoperative assessments will ensure participants meet specific health criteria before enrollment.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 60 with a body mass index between 20 and 30 who are undergoing elective hip replacement surgery.
Not a fit: Patients outside the age range of 18 to 60, those with contraindications to spinal anesthesia, or individuals with certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies that enhance early mobilization after hip replacement surgery.
How similar studies have performed: Previous studies have shown promising results with similar pain management techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults 18 to 60 yrs. old. * Both genders. * ASA I, II. * Body mass index between 20 to 30 kg per meter square. * Height between 160 cm and 180 cm Exclusion Criteria: * Patient refusal. * Age below 18 and above 60 yrs. old. * Uncooperative patients. * Known Allergy to the drugs enrolled in the study. * Body mass index \<30 or \< 20 kg per square meter * Any contraindication of spinal anaesthesia * ASA III, IV patients. * Emergency surgery. * Neuromuscular disorder interferes with sensations in the lower limbs. * Drug abuse or using any drug that modifies pain perception. * Any disability affecting walking capacity rather than the operating joint.
Where this trial is running
Cairo
- Faculty of Medicine- Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Karim Hussein, Md
- Email: karim.ghaleb87@gmail.com
- Phone: 0100741161
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.