Comparing two methods for pain relief after cesarean section

Comparing Quadratus Lumborum Type 1 Block to The Combination Of Intraperitoneal Instillation Of Local Anesthetics And Wound Infiltration For Postoperative Pain After Cesarean Delivery: A Prospective Double-Blind Randomized Controlled Study

Not applicable Interventional Ataturk University · NCT06129032

This study is testing two different ways to manage pain after a cesarean section to see which one helps women recover better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 50 Years
SexFemale
SponsorAtaturk University Academic / other
Locations1 site (Erzurum)
Trial IDNCT06129032 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of two pain management techniques for women undergoing elective cesarean sections. Participants will be randomly assigned to receive either a combination of wound infiltration and intraperitoneal local anesthetic or a quadratus lumborum block for postoperative analgesia. The trial will be conducted in a double-blind manner to ensure unbiased results, following ethical approval and informed consent. The focus is on reducing pain after surgery to improve recovery outcomes for patients.

Who should consider this trial

Good fit: Ideal candidates are pregnant women aged 18 to 50 with ASA II classification, full-term singleton pregnancies scheduled for cesarean delivery.

Not a fit: Patients with contraindications to neuraxial anesthesia, severe obesity, or significant comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for women after cesarean sections.

How similar studies have performed: Previous studies have shown promising results with similar analgesic techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged between 18 to 50
* American Society of Anesthesiologists (ASA) II classification,
* full-term and singleton pregnancies planned to undergo cesarean section
* using Pfannenstiel incision
* spinal anaesthesia

Exclusion Criteria:

* whom neuraxial anaesthesia is contraindicated,
* those who are allergic to drugs to be used in the study,
* who refused to participate in the study,
* those with BMI\>35 kg/m2,
* ASA score ≥3 or higher,
* diabetes mellitus, preeclampsia, cardiovascular disease, chronic pain and neuropathic pain,
* individuals who have received opioids during the surgical procedure for intraoperative pain,
* patients who have undergone abdominal surgery,
* patients who have experienced a transition from spinal anaesthesia to general anaesthesia due to failure,
* those with excessive bleeding during the operation,
* who have uterine atony,
* those who have a drain placed in the area to be infiltrated,
* those who cannot understand the Visual Analog Scale (VAS),
* who have a history of drug addiction and psychiatric disorder

Where this trial is running

Erzurum

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Analgesia
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.