Comparing two methods for nerve block during sinus surgery

Ultrasound-Guided Versus Brainlab Navigation Sphenopalatine Ganglion Block in Functional Endoscopic Sinus Surgery: A Randomized Clinical Trial

Not applicable Interventional Tanta University · NCT06984913

This study is testing which method of giving a nerve block during sinus surgery works better to reduce bleeding and improve comfort for patients.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorTanta University Academic / other
Locations1 site (Tanta, El-Gharbia)
Trial IDNCT06984913 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of ultrasound-guided sphenopalatine ganglion block (SPGB) versus Brainlab navigation SPGB in patients undergoing functional endoscopic sinus surgery (FESS). The goal is to assess which technique better reduces blood loss and improves the surgical field without the use of hypotensive agents. Both methods aim to provide regional anesthesia to enhance patient comfort and surgical outcomes. Participants will be monitored for their response to the nerve block during the procedure.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 undergoing functional endoscopic sinus surgery with ASA physical status I-II.

Not a fit: Patients with severe underlying health conditions, chronic pain requiring major analgesics, or those who are pregnant or lactating may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications during sinus surgery.

How similar studies have performed: Previous studies have shown promise in using ultrasound-guided techniques for nerve blocks, but the comparison with Brainlab navigation is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age from 18 to 65 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I-II.
* Patients undergoing functional endoscopic sinus surgery under general anesthesia.

Exclusion Criteria:

* Patients having a history of severe renal, hepatic, respiratory, cardiac disease, or a neurological condition.
* Drug or alcohol abuse.
* Chronic pain requires major analgesics, sedatives, or corticosteroids.
* Pregnant and lactating women.
* Hypersensitivity to local anesthetic agents.

Where this trial is running

Tanta, El-Gharbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions UltrasoundBrainlab NavigationSphenopalatine Ganglion BlockFunctional Endoscopic Sinus Surgery
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.